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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Electrocardiol
2016 ; 49
(6
): 848-854
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gab.com Text
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English Wikipedia
Electrocardiographic predictors of mortality and sudden cardiac death in patients
with end stage renal disease on hemodialysis
#MMPMID27554424
Waks JW
; Tereshchenko LG
; Parekh RS
J Electrocardiol
2016[Nov]; 49
(6
): 848-854
PMID27554424
show ga
Patients with end stage renal disease (ESRD) on hemodialysis experience a high
incidence of cardiovascular mortality, and sudden cardiac death (SCD) accounts
for approximately 25% of all deaths in this patient population. Despite this high
risk of SCD, many non-invasive SCD risk stratification tools that are frequently
applied to other patient populations (such as those with prior myocardial
infarction and reduced left ventricular systolic function) may be less useful
markers of increased SCD risk in ESRD. Improved SCD risk stratification tools for
use specifically in patients on hemodialysis are therefore necessary to optimally
target use of primary prevention interventions aimed at decreasing SCD incidence.
Electrocardiography is an effective, non-invasive SCD risk stratification tool in
hemodialysis patients. This article reviews data supporting the association
between various ECG parameters (QT interval, spatial QRS-T angle, signal averaged
ECG, heart rate variability, and T-wave alternans) and mortality/SCD in the
dialysis population. Despite the association between abnormal ECG parameters and
SCD, it remains unclear if these abnormal parameters (such as prolonged QT
interval) are mechanistically related to SCD and/or ventricular arrhythmias, or
if they are simply markers for more severe cardiac disease, such as left
ventricular hypertrophy, that may independently predispose to SCD. Current
obstacles that impair widespread implementation of ECG risk stratification in the
hemodialysis population are also discussed.
|Cardiac Conduction System Disease/*diagnosis/*mortality
[MESH]
|Causality
[MESH]
|Comorbidity
[MESH]
|Death, Sudden, Cardiac/*epidemiology
[MESH]
|Electrocardiography/methods/*statistics & numerical data
[MESH]