Tuft Cells: New Players in Colitis #MMPMID27717671
Steele SP; Melchor SJ; Petri WA
Trends Mol Med 2016[Nov]; 22 (11): 921-4 PMID27717671show ga
A recent surge of interest in tuft cells, which are chemosensory intestinal epithelial cells, has uncovered new functional roles for these cells in colorectal cancer, metabolic signaling, and type 2 immunity. Here, we explore emerging evidence suggesting that tuft cells are critical for protection during enteric infections and inflammatory responses.