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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Atr+Fibrillation
2013 ; 5
(6
): 645
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Emergency Physician Patterns Related to Anticoagulation of Patients with
Recent-Onset Atrial Fibrillation and Flutter
#MMPMID28496821
Misra P
; Lang E
; Clement CM
; Brison RJ
; Rowe BH
; Borgundvaag B
; Langhan T
; Magee K
; Stenstrom R
; Perry JJ
; Birnie D
; Wells GA
; Xue X
; Innes G
; Stiell IG
J Atr Fibrillation
2013[Apr]; 5
(6
): 645
PMID28496821
show ga
Guidelines strongly recommend long-term anticoagulation with warfarin for
patients with newly recognized AF who have high embolic risk by virtue of a
CHADS(2) (Congestive Heart Failure, Hypertension, Age >65, Diabetes, History of
Stroke) score ? 2. The goal of this study was to determine patterns of emergency
department-initiated anticoagulation among eligible patients discharged from
Canadian centers with an episode of recent-onset atrial fibrillation and flutter
(RAFF) and determine if decision-making is driven by the CHADS(2) score or other
factors. This was accomplished by examining health records using uniform case
identification and data abstraction as well as centralized quality control; it
was conducted in 8 Canadian university emergency departments over a 12-month
period. Eligible patients for this analysis demonstrated RAFF requiring emergency
management, were not already taking warfarin and were not admitted to hospital.
Univariate analyses were conducted using T-test or Chi-square to select factors
associated with anticoagulation initiation at a significance level of p < 0.15
and multiple logistic regression was employed to evaluate independent predictors
after adjustment for confounders. Among 633 eligible patients, only 21 out of 120
patients (18%) with a CHADS(2) score ? 2 received anticoagulation and among 70
patients who were given anticoagulation only 21 (30%) had a CHADS(2) score ? 2.
Independent predictors of anticoagulation included age by 10-year strata: (OR =
1.7; 95% CI 1.3 - 2.1), heparin use in the anticoagulation (OR = 9.6; 95% CI 4.9
- 18.9), a new prescription for metoprolol (OR = 9.6; 95% CI 4.9 - 18.9) and
being referred to cardiology for follow-up (OR = 5.6; 95% CI 2.6 - 12.0).
CHADS(2) ? 2 doubled the likelihood of being prescribed anticoagulation (OR= 2.0;
95% CI 1.5 - 3.5) but was not an independent predictor. It was thus determined
that patients discharged from the emergency department in this study were not
prescribed anticoagulation in keeping with current recommendations. This practice
gap merits further investigation and may benefit from educational efforts or
enhanced support for anticoagulation use from the emergency department.