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10.1083/jcb.201605093 http://scihub22266oqcxt.onion/10.1083/jcb.201605093 C5147001!5147001 !27903607     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27903607 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Cell+Biol 2016 ; 215 (5 ): 649-665 Nephropedia Template TP {{tp|p=27903607 |t=2016. Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy |pdf=|usr=}}{{27903607 }} gab.com Text Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy JO: J Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=27903607 #FOAvip Mitophagy is thought to play an important role in mitochondrial quality control. Mitochondrial division is believed to occur first, and autophagosome formation subsequently occurs to enwrap mitochondria as a process of mitophagy. However, there has not been any temporal analysis of mitochondrial division and autophagosome formation in mitophagy. Therefore, the relationships among these processes remain unclear. We show that the mitochondrial division factor Dnm1 in yeast or Drp1 in mammalian cells is dispensable for mitophagy. Autophagosome formation factors, such as FIP200, ATG14, and WIPIs, were essential for the mitochondrial division for mitophagy. Live-cell imaging showed that isolation membranes formed on the mitochondria. A small portion of the mitochondria then divided from parental mitochondria simultaneously with the extension of isolation membranes and autophagosome formation. These findings suggest the presence of a mitophagy process in which mitochondrial division for mitophagy is accomplished together with autophagosome formation. Twit Text FOAVip Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy ????J Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=27903607 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27903607 #FOAvip English Wikipedia <ref>{{Cite pmid|27903607 }}</ref> Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy #MMPMID27903607 Yamashita SI ; Jin X ; Furukawa K ; Hamasaki M ; Nezu A ; Otera H ; Saigusa T ; Yoshimori T ; Sakai Y ; Mihara K ; Kanki T J Cell Biol 2016[Dec]; 215 (5 ): 649-665 PMID27903607 show ga Mitophagy is thought to play an important role in mitochondrial quality control. Mitochondrial division is believed to occur first, and autophagosome formation subsequently occurs to enwrap mitochondria as a process of mitophagy. However, there has not been any temporal analysis of mitochondrial division and autophagosome formation in mitophagy. Therefore, the relationships among these processes remain unclear. We show that the mitochondrial division factor Dnm1 in yeast or Drp1 in mammalian cells is dispensable for mitophagy. Autophagosome formation factors, such as FIP200, ATG14, and WIPIs, were essential for the mitochondrial division for mitophagy. Live-cell imaging showed that isolation membranes formed on the mitochondria. A small portion of the mitochondria then divided from parental mitochondria simultaneously with the extension of isolation membranes and autophagosome formation. These findings suggest the presence of a mitophagy process in which mitochondrial division for mitophagy is accomplished together with autophagosome formation. |*Mitophagy/drug effects [MESH] |Animals [MESH] |Autophagosomes/drug effects/*metabolism/ultrastructure [MESH] |Deferiprone [MESH] |Dynamins [MESH] |GTP Phosphohydrolases/*metabolism [MESH] |HeLa Cells [MESH] |Humans [MESH] |Mammals/metabolism [MESH] |Microtubule-Associated Proteins/*metabolism [MESH] |Mitochondrial Membranes/drug effects/metabolism [MESH] |Mitochondrial Proteins/*metabolism [MESH] |Models, Biological [MESH] |Pyridones/pharmacology [MESH] |Saccharomyces cerevisiae Proteins/metabolism [MESH] |Saccharomyces cerevisiae/cytology/drug effects/metabolism/ultrastructure [MESH]Mitochondrial division occurs concurrently with autophagosome formatio(epmc).pdf DeepDyve Pubget Overpricing