Prevention of breast cancer by RANKL/RANK blockade #MMPMID27325297
Galluzzi L; Buqué A; Kroemer G
Cell Res 2016[Jul]; 26 (7): 751-2 PMID27325297show ga
Robust genetic evidence in mice and humans indicates that RANK signaling plays a major role in mammary carcinogenesis driven by BRCA1/BRCA2 mutations. These findings may inaugurate a new era of breast cancer prevention, changing the life of millions of women worldwide.