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10.1093/bmb/ldw020 http://scihub22266oqcxt.onion/10.1093/bmb/ldw020 C5127428!5127428!27151958     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Br+Med+Bull 2016 ; 118 (1): 149-58 Nephropedia Template TP {{tp|p=27151958|t=2016. Collagenase clostridium histolyticum in Dupuytren s contracture: a systematic review |pdf=|usr=}}{{27151958}} gab.com Text Collagenase clostridium histolyticum in Dupuytren s contracture: a systematic review JO: Br Med Bull http://www.kidney.de/pget.php?&tw=1&pmid=27151958 #FOAvip Introduction: In the last few years, the use of collagenase clostridium histolyticum for management of Dupuytren's contracture has increased. The procedure of enzymatic fasciectomy has become popular because it is non-invasive, safe and fast to perform. Sources of data: A systematic search was performed on Medline (PubMed), Web of Science and Scopus databases using the combined keywords ?Dupuytren collagenase? and ?Dupuytren clostridium histolyticum?. Forty-three studies were identified. The quality of the studies was assessed using the Coleman Methodological Score. Areas of agreement: The use of collagenase clostridium histolyticum provides better outcomes in patients with mild-moderate joint contracture, with lower complications and side effects than open fasciectomy. Manipulation can be performed 2?7 days after the injection. The use of collagenase is cost-effective. Areas of controversy: Most of the studies did not report patient-related outcomes. The role of dynamic splint has to be investigated with randomized clinical trials. Growing points: The shorter recovery time and the low incidence of serious or major adverse effects are the main advantages of this new technology. Areas timely for developing research: There is a need to perform studies with longer follow-up because the recurrence rate seems to increase with time. Further investigations are necessary to assess whether it is safe and effective to inject two or more cords at the same time. Twit Text FOAVip Collagenase clostridium histolyticum in Dupuytren s contracture: a systematic review ????Br Med Bull http://www.kidney.de/pget.php?&tw=1&pmid=27151958 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27151958 #FOAvip English Wikipedia <ref>{{Cite pmid|27151958}}</ref> Collagenase clostridium histolyticum in Dupuytren s contracture: a systematic review #MMPMID27151958 Smeraglia F; Del Buono A; Maffulli N Br Med Bull 2016[Jun]; 118 (1): 149-58 PMID27151958show ga Introduction: In the last few years, the use of collagenase clostridium histolyticum for management of Dupuytren's contracture has increased. The procedure of enzymatic fasciectomy has become popular because it is non-invasive, safe and fast to perform. Sources of data: A systematic search was performed on Medline (PubMed), Web of Science and Scopus databases using the combined keywords ?Dupuytren collagenase? and ?Dupuytren clostridium histolyticum?. Forty-three studies were identified. The quality of the studies was assessed using the Coleman Methodological Score. Areas of agreement: The use of collagenase clostridium histolyticum provides better outcomes in patients with mild-moderate joint contracture, with lower complications and side effects than open fasciectomy. Manipulation can be performed 2?7 days after the injection. The use of collagenase is cost-effective. Areas of controversy: Most of the studies did not report patient-related outcomes. The role of dynamic splint has to be investigated with randomized clinical trials. Growing points: The shorter recovery time and the low incidence of serious or major adverse effects are the main advantages of this new technology. Areas timely for developing research: There is a need to perform studies with longer follow-up because the recurrence rate seems to increase with time. Further investigations are necessary to assess whether it is safe and effective to inject two or more cords at the same time. äCollagenase clostridium histolyticum in Dupuytren s contracture: a sys(epmc).pdf DeepDyve Pubget Overpricing