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10.1093/bmb/ldw009 http://scihub22266oqcxt.onion/10.1093/bmb/ldw009 C5127417!5127417!26983962     free     free     free       Br+Med+Bull 2016 ; 118 (1): 50-63 Nephropedia Template TP {{tp|p=26983962|t=2016. Chronic granulomatous disease |pdf=|usr=}}{{26983962}} gab.com Text Chronic granulomatous disease JO: Br Med Bull http://www.kidney.de/pget.php?&tw=1&pmid=26983962 #FOAvip Introduction: Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by recurrent, life-threatening bacterial and fungal infections of the skin, the airways, the lymph nodes, the liver, the brain and the bones. Frequently found pathogens are Staphylococcus aureus, Aspergillus species, Klebsiella species, Burkholderia cepacia, Serratia marcescens and Salmonella species. Sources of data: CGD is a rare (?1:250 000 individuals) disease caused by mutations in any one of the five components of the NADPH oxidase in phagocytic leucocytes. This enzyme generates superoxide and is essential for intracellular killing of pathogens by phagocytes. Areas of agreement: CGD patients suffer not only from life-threatening infections, but also from excessive inflammatory reactions. Areas of controversy: Neither the cause of these inflammatory reactions nor the way to treat them is clear. Areas timely for developing research: Patient selection for and timing of bone marrow transplantation along with gene therapy. Twit Text FOAVip Chronic granulomatous disease ????Br Med Bull http://www.kidney.de/pget.php?&tw=1&pmid=26983962 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26983962 #FOAvip English Wikipedia <ref>{{Cite pmid|26983962}}</ref> Chronic granulomatous disease #MMPMID26983962 Roos D Br Med Bull 2016[Jun]; 118 (1): 50-63 PMID26983962show ga Introduction: Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by recurrent, life-threatening bacterial and fungal infections of the skin, the airways, the lymph nodes, the liver, the brain and the bones. Frequently found pathogens are Staphylococcus aureus, Aspergillus species, Klebsiella species, Burkholderia cepacia, Serratia marcescens and Salmonella species. Sources of data: CGD is a rare (?1:250 000 individuals) disease caused by mutations in any one of the five components of the NADPH oxidase in phagocytic leucocytes. This enzyme generates superoxide and is essential for intracellular killing of pathogens by phagocytes. Areas of agreement: CGD patients suffer not only from life-threatening infections, but also from excessive inflammatory reactions. Areas of controversy: Neither the cause of these inflammatory reactions nor the way to treat them is clear. Areas timely for developing research: Patient selection for and timing of bone marrow transplantation along with gene therapy. äChronic granulomatous disease (epmc).pdf DeepDyve Pubget Overpricing