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10.1073/pnas.1613113113 http://scihub22266oqcxt.onion/10.1073/pnas.1613113113 C5127329!5127329!27821771     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2016 ; 113 (47): 13414-9 Nephropedia Template TP {{tp|p=27821771|t=2016. Regulation of embryonic neurogenesis by germinal zone vasculature |pdf=|usr=}}{{27821771}} gab.com Text Regulation of embryonic neurogenesis by germinal zone vasculature JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=27821771 #FOAvip Neural progenitor cells (NPCs) proliferate to generate precursors for new neurons. To sustain this process, NPCs balance self-renewal with the generation of progeny committed to neuronal differentiation. In the adult mammalian brain, blood vessels and vessel-derived factors help regulate this balance by modulating NPC proliferation and quiescence, independently of vascular roles in providing oxygen and nutrients. In contrast, it has been proposed that vasculature regulates NPC behavior in the developing forebrain by alleviating tissue hypoxia. We show here that germinal zone vasculature in the embryonic hindbrain regulates the balance of NPC self-renewal with neuron production, independently of roles in tissue oxygenation. Information on how blood vessels regulate neurogenesis may aid in the design of therapies for brain regeneration in injury and disease. Twit Text FOAVip Regulation of embryonic neurogenesis by germinal zone vasculature ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=27821771 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27821771 #FOAvip English Wikipedia <ref>{{Cite pmid|27821771}}</ref> Regulation of embryonic neurogenesis by germinal zone vasculature #MMPMID27821771 Tata M; Wall I; Joyce A; Vieira JM; Kessaris N; Ruhrberg C Proc Natl Acad Sci U S A 2016[Nov]; 113 (47): 13414-9 PMID27821771show ga Neural progenitor cells (NPCs) proliferate to generate precursors for new neurons. To sustain this process, NPCs balance self-renewal with the generation of progeny committed to neuronal differentiation. In the adult mammalian brain, blood vessels and vessel-derived factors help regulate this balance by modulating NPC proliferation and quiescence, independently of vascular roles in providing oxygen and nutrients. In contrast, it has been proposed that vasculature regulates NPC behavior in the developing forebrain by alleviating tissue hypoxia. We show here that germinal zone vasculature in the embryonic hindbrain regulates the balance of NPC self-renewal with neuron production, independently of roles in tissue oxygenation. Information on how blood vessels regulate neurogenesis may aid in the design of therapies for brain regeneration in injury and disease. äRegulation of embryonic neurogenesis by germinal zone vasculature (epmc).pdf DeepDyve Pubget Overpricing