Coordinated Tumor Suppression by Chromosome 8p #MMPMID27165739
Tschaharganeh DF; Bosbach B; Lowe SW
Cancer Cell 2016[May]; 29 (5): 617-9 PMID27165739show ga
In this issue of Cancer Cell, Cai et al. use genome editing to study 8p deletions in a mammary epithelial cell model and show that 8p loss of heterozygosity (LOH) attenuates the action of several genes that collectively promote cell invasion and enhance cellular sensitivity to autophagy inhibitors.