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10.1038/onc.2016.104 http://scihub22266oqcxt.onion/10.1038/onc.2016.104 C5119456!5119456!27086930     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncogene 2016 ; 35 (46): 5931-41 Nephropedia Template TP {{tp|p=27086930|t=2016. Damage-associated molecular patterns in cancer: A double-edged sword |pdf=|usr=}}{{27086930}} gab.com Text Damage-associated molecular patterns in cancer: A double-edged sword JO: Oncogene http://www.kidney.de/pget.php?&tw=1&pmid=27086930 #FOAvip Damage-associated molecular patterns (DAMPs) are released in response to cell death and stress, and are potent triggers of sterile inflammation. Recent evidence suggests that DAMPs may also have a key role in the development of cancer as well as in the host response to cytotoxic anti-tumor therapy. As such, DAMPs may exert protective functions by alerting the immune system to the presence of dying tumor cells, thereby triggering immunogenic tumor cell death. On the other hand, cell death and release of DAMPs may also trigger chronic inflammation and thereby promote the development or progression of tumors. Here, we will review the contribution of candidate DAMPs and their receptors and discuss the evidence for DAMPs as tumor-promoting and anti-tumor effectors as well as unsolved questions such as DAMP release from non-tumor cells as well as the existence of tumor-specific DAMPs. Twit Text FOAVip Damage-associated molecular patterns in cancer: A double-edged sword ????Oncogene http://www.kidney.de/pget.php?&tw=1&pmid=27086930 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27086930 #FOAvip English Wikipedia <ref>{{Cite pmid|27086930}}</ref> Damage-associated molecular patterns in cancer: A double-edged sword #MMPMID27086930 Hernandez C; Huebener P; Schwabe RF Oncogene 2016[Nov]; 35 (46): 5931-41 PMID27086930show ga Damage-associated molecular patterns (DAMPs) are released in response to cell death and stress, and are potent triggers of sterile inflammation. Recent evidence suggests that DAMPs may also have a key role in the development of cancer as well as in the host response to cytotoxic anti-tumor therapy. As such, DAMPs may exert protective functions by alerting the immune system to the presence of dying tumor cells, thereby triggering immunogenic tumor cell death. On the other hand, cell death and release of DAMPs may also trigger chronic inflammation and thereby promote the development or progression of tumors. Here, we will review the contribution of candidate DAMPs and their receptors and discuss the evidence for DAMPs as tumor-promoting and anti-tumor effectors as well as unsolved questions such as DAMP release from non-tumor cells as well as the existence of tumor-specific DAMPs. äDamage-associated molecular patterns in cancer: A double-edged sword (epmc).pdf DeepDyve Pubget Overpricing