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10.1523/ENEURO.0205-16.2016 http://scihub22266oqcxt.onion/10.1523/ENEURO.0205-16.2016 C5114701!5114701!27896314     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       eNeuro 2016 ; 3 (6): ä Nephropedia Template TP {{tp|p=27896314|t=2016. Graph Theoretic and Motif Analyses of the Hippocampal Neuron Type Potential Connectome |pdf=|usr=}}{{27896314}} gab.com Text Graph Theoretic and Motif Analyses of the Hippocampal Neuron Type Potential Connectome JO: eNeuro http://www.kidney.de/pget.php?&tw=1&pmid=27896314 #FOAvip We computed the potential connectivity map of all known neuron types in the rodent hippocampal formation by supplementing scantly available synaptic data with spatial distributions of axons and dendrites from the open-access knowledge base Hippocampome.org. The network that results from this endeavor, the broadest and most complete for a mammalian cortical region at the neuron-type level to date, contains more than 3200 connections among 122 neuron types across six subregions. Analyses of these data using graph theory metrics unveil the fundamental architectural principles of the hippocampal circuit. Globally, we identify a highly specialized topology minimizing communication cost; a modular structure underscoring the prominence of the trisynaptic loop; a core set of neuron types serving as information-processing hubs as well as a distinct group of particular antihub neurons; a nested, two-tier rich club managing much of the network traffic; and an innate resilience to random perturbations. At the local level, we uncover the basic building blocks, or connectivity patterns, that combine to produce complex global functionality, and we benchmark their utilization in the circuit relative to random networks. Taken together, these results provide a comprehensive connectivity profile of the hippocampus, yielding novel insights on its functional operations at the computationally crucial level of neuron types. Twit Text FOAVip Graph Theoretic and Motif Analyses of the Hippocampal Neuron Type Potential Connectome ????eNeuro http://www.kidney.de/pget.php?&tw=1&pmid=27896314 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27896314 #FOAvip English Wikipedia <ref>{{Cite pmid|27896314}}</ref> Graph Theoretic and Motif Analyses of the Hippocampal Neuron Type Potential Connectome #MMPMID27896314 Rees CL; Wheeler DW; Hamilton DJ; White CM; Komendantov AO; Ascoli GA eNeuro 2016[Nov]; 3 (6): ä PMID27896314show ga We computed the potential connectivity map of all known neuron types in the rodent hippocampal formation by supplementing scantly available synaptic data with spatial distributions of axons and dendrites from the open-access knowledge base Hippocampome.org. The network that results from this endeavor, the broadest and most complete for a mammalian cortical region at the neuron-type level to date, contains more than 3200 connections among 122 neuron types across six subregions. Analyses of these data using graph theory metrics unveil the fundamental architectural principles of the hippocampal circuit. Globally, we identify a highly specialized topology minimizing communication cost; a modular structure underscoring the prominence of the trisynaptic loop; a core set of neuron types serving as information-processing hubs as well as a distinct group of particular antihub neurons; a nested, two-tier rich club managing much of the network traffic; and an innate resilience to random perturbations. At the local level, we uncover the basic building blocks, or connectivity patterns, that combine to produce complex global functionality, and we benchmark their utilization in the circuit relative to random networks. Taken together, these results provide a comprehensive connectivity profile of the hippocampus, yielding novel insights on its functional operations at the computationally crucial level of neuron types. äGraph Theoretic and Motif Analyses of the Hippocampal Neuron Type Pote(epmc).pdf DeepDyve Pubget Overpricing