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10.1016/j.dnarep.2015.09.014 http://scihub22266oqcxt.onion/10.1016/j.dnarep.2015.09.014 C5113751!5113751!26429064     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       DNA+Repair+(Amst) 2015 ; 36 (ä): 114-21 Nephropedia Template TP {{tp|p=26429064|t=2015. Chromatin dynamics after DNA damage: the legacy of the Access-Repair-Restore model |pdf=|usr=}}{{26429064}} gab.com Text Chromatin dynamics after DNA damage: the legacy of the Access-Repair-Restore model JO: DNA Repair (Amst) http://www.kidney.de/pget.php?&tw=1&pmid=26429064 #FOAvip Eukaryotic genomes are packaged into chromatin, which is the physiological substrate for all DNA transactions, including DNA damage and repair. Chromatin organization imposes major constraints on DNA damage repair and thus undergoes critical rearrangements during the repair process. These rearrangements have been integrated into the ?Access-Repair-Restore? (ARR) model, which provides a molecular framework for chromatin dynamics in response to DNA damage. Here, we take a historical perspective on the elaboration of this model and describe the molecular players involved in damaged chromatin reorganization in human cells. In particular, we present our current knowledge of chromatin assembly coupled to DNA damage repair, focusing on the role of histone variants and their dedicated chaperones. Finally, we discuss the impact of chromatin rearrangements after DNA damage on chromatin function and epigenome maintenance. Twit Text FOAVip Chromatin dynamics after DNA damage: the legacy of the Access-Repair-Restore model ????DNA Repair (Amst) http://www.kidney.de/pget.php?&tw=1&pmid=26429064 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26429064 #FOAvip English Wikipedia <ref>{{Cite pmid|26429064}}</ref> Chromatin dynamics after DNA damage: the legacy of the Access-Repair-Restore model #MMPMID26429064 Polo SE; Almouzni G DNA Repair (Amst) 2015[Dec]; 36 (ä): 114-21 PMID26429064show ga Eukaryotic genomes are packaged into chromatin, which is the physiological substrate for all DNA transactions, including DNA damage and repair. Chromatin organization imposes major constraints on DNA damage repair and thus undergoes critical rearrangements during the repair process. These rearrangements have been integrated into the ?Access-Repair-Restore? (ARR) model, which provides a molecular framework for chromatin dynamics in response to DNA damage. Here, we take a historical perspective on the elaboration of this model and describe the molecular players involved in damaged chromatin reorganization in human cells. In particular, we present our current knowledge of chromatin assembly coupled to DNA damage repair, focusing on the role of histone variants and their dedicated chaperones. Finally, we discuss the impact of chromatin rearrangements after DNA damage on chromatin function and epigenome maintenance. äChromatin dynamics after DNA damage: the legacy of the Access-Repair-R(epmc).pdf DeepDyve Pubget Overpricing