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10.1210/jc.2013-3450 http://scihub22266oqcxt.onion/10.1210/jc.2013-3450 C5112012!5112012!24423304     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Endocrinol+Metab 2014 ; 99 (3): 757-67 Nephropedia Template TP {{tp|p=24423304|t=2014. Efficacy of Vitamin D Supplementation in Depression in Adults: A Systematic Review |pdf=|usr=}}{{24423304}} gab.com Text Efficacy of Vitamin D Supplementation in Depression in Adults: A Systematic Review JO: J Clin Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=24423304 #FOAvip Context: Randomized controlled trials (RCTs) investigating the efficacy of vitamin D (Vit D) in depression provided inconsistent results. Objective: We aim to summarize the evidence of RCTs to assess the efficacy of oral Vit D supplementation in depression compared to placebo. Data Sources: We searched electronic databases, two conference proceedings, and gray literature by contacting authors of included studies. Study Selection: We selected parallel RCTs investigating the effect of oral Vit D supplementation compared with placebo on depression in adults at risk of depression, with depression symptoms or a primary diagnosis of depression. Data Extraction: Two reviewers independently extracted data from relevant literature. Data Synthesis: Classical and Bayesian random-effects meta-analyses were used to pool relative risk, odds ratio, and standardized mean difference. The quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation tool. Results: Six RCTs were identified with 1203 participants (72% females) including 71 depressed patients; five of the studies involved adults at risk of depression, and one trial used depressed patients. Results of the classical meta-analysis showed no significant effect of Vit D supplementation on postintervention depression scores (standardized mean difference = ?0.14, 95% confidence interval =?0.41 to 0.13, P =.32; odds ratio =0.93, 95% confidence interval =0.54 to 1.59, P = .79). The quality of evidence was low. No significant differences were demonstrated in subgroup or sensitivity analyses. Similar results were found when Bayesian meta-analyses were applied. Conclusions: There is insufficient evidence to support the efficacy of Vit D supplementation in depression symptoms, and more RCTs using depressed patients are warranted. Twit Text FOAVip Efficacy of Vitamin D Supplementation in Depression in Adults: A Systematic Review ????J Clin Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=24423304 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24423304 #FOAvip English Wikipedia <ref>{{Cite pmid|24423304}}</ref> Efficacy of Vitamin D Supplementation in Depression in Adults: A Systematic Review #MMPMID24423304 Li G; Mbuagbaw L; Samaan Z; Falavigna M; Zhang S; Adachi JD; Cheng J; Papaioannou A; Thabane L J Clin Endocrinol Metab 2014[Mar]; 99 (3): 757-67 PMID24423304show ga Context: Randomized controlled trials (RCTs) investigating the efficacy of vitamin D (Vit D) in depression provided inconsistent results. Objective: We aim to summarize the evidence of RCTs to assess the efficacy of oral Vit D supplementation in depression compared to placebo. Data Sources: We searched electronic databases, two conference proceedings, and gray literature by contacting authors of included studies. Study Selection: We selected parallel RCTs investigating the effect of oral Vit D supplementation compared with placebo on depression in adults at risk of depression, with depression symptoms or a primary diagnosis of depression. Data Extraction: Two reviewers independently extracted data from relevant literature. Data Synthesis: Classical and Bayesian random-effects meta-analyses were used to pool relative risk, odds ratio, and standardized mean difference. The quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation tool. Results: Six RCTs were identified with 1203 participants (72% females) including 71 depressed patients; five of the studies involved adults at risk of depression, and one trial used depressed patients. Results of the classical meta-analysis showed no significant effect of Vit D supplementation on postintervention depression scores (standardized mean difference = ?0.14, 95% confidence interval =?0.41 to 0.13, P =.32; odds ratio =0.93, 95% confidence interval =0.54 to 1.59, P = .79). The quality of evidence was low. No significant differences were demonstrated in subgroup or sensitivity analyses. Similar results were found when Bayesian meta-analyses were applied. Conclusions: There is insufficient evidence to support the efficacy of Vit D supplementation in depression symptoms, and more RCTs using depressed patients are warranted. äEfficacy of Vitamin D Supplementation in Depression in Adults: A Syste(epmc).pdf DeepDyve Pubget Overpricing