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10.1155/2016/2794364 http://scihub22266oqcxt.onion/10.1155/2016/2794364 C5110877!5110877 !27882047     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27882047 &cmd=llinks): Failed to open stream: HTTP request failed! 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Perioperative Elevation in Cell-Free DNA Levels in Patients Undergoing Cardiac Surgery: Possible Contribution of Neutrophil Extracellular Traps to Perioperative Renal Dysfunction |pdf=|usr=}}{{27882047 }} gab.com Text Perioperative Elevation in Cell-Free DNA Levels in Patients Undergoing Cardiac Surgery: Possible Contribution of Neutrophil Extracellular Traps to Perioperative Renal Dysfunction JO: Anesthesiol Res Pract http://www.kidney.de/pget.php?&tw=1&pmid=27882047 #FOAvip Background. This study aimed to determine the perioperative change in serum double-strand DNA (dsDNA) as a marker potentially reflecting neutrophil extracellular trap concentration in samples from patients undergoing cardiac surgery and to analyze a relationship between serum dsDNA concentrations and perioperative renal dysfunction. Methods. Serum dsDNA concentrations in samples that were collected during a previously conducted, prospective, multicenter, observational study were measured. Eighty patients undergoing elective cardiac surgery were studied. Serum samples were collected at baseline, immediately after surgery, and the day after surgery (POD-1). Results. Serum dsDNA concentration was significantly increased from baseline (median, 398?ng/mL [interquartile range, 372-475?ng/mL]) to immediately after surgery (median, 540?ng/mL [437-682?ng/mL], p < 0.001), and they were reduced by POD-1 (median, 323?ng/mL [256-436?ng/mL]). The difference in serum creatinine concentration between baseline and POD-1 was correlated with dsDNA concentration on POD-1 (r(s) = 0.61, p < 0.001). Conclusions. In patients undergoing cardiac surgery, serum dsDNA concentration is elevated postoperatively. Prolonged elevation in dsDNA concentration is correlated with perioperative renal dysfunction. Further large-scale studies are needed to determine the relationship between serum concentration of circulating dsDNA and perioperative renal dysfunction. Twit Text FOAVip Perioperative Elevation in Cell-Free DNA Levels in Patients Undergoing Cardiac Surgery: Possible Contribution of Neutrophil Extracellular Traps to Perioperative Renal Dysfunction ????Anesthesiol Res Pract http://www.kidney.de/pget.php?&tw=1&pmid=27882047 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27882047 #FOAvip English Wikipedia <ref>{{Cite pmid|27882047 }}</ref> Perioperative Elevation in Cell-Free DNA Levels in Patients Undergoing Cardiac Surgery: Possible Contribution of Neutrophil Extracellular Traps to Perioperative Renal Dysfunction #MMPMID27882047 Qi Y ; Uchida T ; Yamamoto M ; Yamamoto Y ; Kido K ; Ito H ; Ohno N ; Asahara M ; Yamada Y ; Yamaguchi O ; Mitaka C ; Tomita M ; Makita K Anesthesiol Res Pract 2016[]; 2016 (ä): 2794364 PMID27882047 show ga Background. This study aimed to determine the perioperative change in serum double-strand DNA (dsDNA) as a marker potentially reflecting neutrophil extracellular trap concentration in samples from patients undergoing cardiac surgery and to analyze a relationship between serum dsDNA concentrations and perioperative renal dysfunction. Methods. Serum dsDNA concentrations in samples that were collected during a previously conducted, prospective, multicenter, observational study were measured. Eighty patients undergoing elective cardiac surgery were studied. Serum samples were collected at baseline, immediately after surgery, and the day after surgery (POD-1). Results. Serum dsDNA concentration was significantly increased from baseline (median, 398?ng/mL [interquartile range, 372-475?ng/mL]) to immediately after surgery (median, 540?ng/mL [437-682?ng/mL], p < 0.001), and they were reduced by POD-1 (median, 323?ng/mL [256-436?ng/mL]). The difference in serum creatinine concentration between baseline and POD-1 was correlated with dsDNA concentration on POD-1 (r(s) = 0.61, p < 0.001). Conclusions. In patients undergoing cardiac surgery, serum dsDNA concentration is elevated postoperatively. Prolonged elevation in dsDNA concentration is correlated with perioperative renal dysfunction. Further large-scale studies are needed to determine the relationship between serum concentration of circulating dsDNA and perioperative renal dysfunction. äPerioperative Elevation in Cell-Free DNA Levels in Patients Undergoing(epmc).pdf DeepDyve Pubget Overpricing