Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27789133&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Ann+Epidemiol 2016 ; 26 (11): 780-787.e1 Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Racial differences in renal replacement therapy initiation among children with a non-glomerular cause of chronic kidney disease #MMPMID27789133
Ng DK; Moxey-Mims M; Warady BA; Furth SL; Muņoz A
Ann Epidemiol 2016[Nov]; 26 (11): 780-787.e1 PMID27789133show ga
Purpose: African American (AA) adults with chronic kidney disease (CKD) have a faster progression to end stage renal disease (ESRD) and are less likely to receive a kidney transplant. It is unclear whether AA children experience renal replacement therapy (RRT) for ESRD sooner than non-AA children after accounting for socioeconomic status (SES). Methods: Among children with non-glomerular CKD in the Chronic Kidney Disease in Children (CKiD) study, we investigated time to RRT (i.e., first dialysis or transplant) after CKD onset using parametric survival models and accounted for SES differences by inverse probability weights (IPWs). Results: Of 110 AA and 493 non-AA children (median age= 10 years), AA children had shorter time to first RRT: median time was 3.2 years earlier than non-AA children (95%CI: ?6.1, ?0.3). When accounting for SES, this difference was diminished and non-significant (?1.6 years; 95%CI: ?4.6, +1.5) and its directionality was consistent with faster GFR decline among AA children (?6.2% vs. ?4.4% per year, p= 0.098). When RRT was deconstructed into dialysis or transplant, the time to dialysis was 37.5% shorter for AA children and 53.7% longer for transplant. These inferences were confirmed by the frequency and timing of transplant after initiating dialysis. Conclusions: Racial differences in time to RRT were almost fully accounted for by SES and the remaining difference was congruent with a faster GFR decline among AA children. Access to transplant occurred later, yet times to dialysis were shorter among AA children even when accounting for SES which may be due to a lack of organ availability.