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10.1084/jem.20160560

http://scihub22266oqcxt.onion/10.1084/jem.20160560
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C5110020!5110020!27810925
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suck abstract from ncbi


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pmid27810925      J+Exp+Med 2016 ; 213 (12): 2691-706
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  • CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP #MMPMID27810925
  • Akatsu C; Shinagawa K; Numoto N; Liu Z; Ucar AK; Aslam M; Phoon S; Adachi T; Furukawa K; Ito N; Tsubata T
  • J Exp Med 2016[Nov]; 213 (12): 2691-706 PMID27810925show ga
  • Akatsu and colleagues show that CD72 specifically recognizes Sm/RNP, a lupus-related self-antigen and an endogenous TLR7 ligand, and inhibits B cell responses to Sm/RNP. In mice, CD72 prevents production of anti-Sm/RNP antibodies crucial for lupus development.
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