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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Intern+Med 2016 ; 55 (20): 3047-51 Nephropedia Template TP
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Successful Corticosteroid Treatment for Purpura Fulminans Associated with Quinolone #MMPMID27746448
Okamura I; Nakamura Y; Katsurada Y; Sato K; Ikeda T; Kimura F
Intern Med 2016[Oct]; 55 (20): 3047-51 PMID27746448show ga
Purpura fulminans (PF) is a life-threatening syndrome comprising progressive hemorrhagic necrosis due to disseminated intravascular coagulation and dermal vascular thrombosis that leads to purpura and tissue necrosis. Various therapies have been used to arrest the progression of this disease, however, there is no established treatment because of the variety of underlying causes. We herein present an adult case of PF associated with leukocytoclastic vasculitis triggered by antibiotic (levofloxacin) intake. As a result of our rapid and accurate identification of the underlying cause, corticosteroid therapy successfully repressed the inflammatory process. As far as we know, this is the first report of levofloxacin-associated PF.