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10.1007/s12020-016-1092-5 http://scihub22266oqcxt.onion/10.1007/s12020-016-1092-5 C5107201!5107201 !27709474     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27709474 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Endocrine 2016 ; 54 (3 ): 642-647 Nephropedia Template TP {{tp|p=27709474 |t=2016. Identifying the culprit lesion in tumor induced hypophosphatemia, the solution of a clinical enigma |pdf=|usr=}}{{27709474 }} gab.com Text Identifying the culprit lesion in tumor induced hypophosphatemia, the solution of a clinical enigma JO: Endocrine http://www.kidney.de/pget.php?&tw=1&pmid=27709474 #FOAvip Tumor-induced osteomalacia is a rare acquired metabolic bone disorder characterized by isolated renal phosphate wasting due to abnormal tumor production of fibroblast growth factor 23. We report the case of a 59 year old woman referred to our department with a long history of progressive diffuse muscle weakness and pain, generalized bone pains and multiple insufficiency fractures of heels, ankles and hips due to a hypophosphatemic osteomalacia. A fibroblast growth factor 23-producing phosphaturic mesenchymal tumor localized in the left quadriceps femoris muscle was identified 7 years after onset of symptoms. Excision of the tumor resulted in normalization of serum phosphate and fibroblast growth factor 23 levels and in complete resolution of the clinical picture with disappearance of all musculoskeletal symptoms. This case illustrates the diagnostic difficulties in establishing a diagnosis tumor-induced osteomalacia and in identifying the responsible tumor. Our case underscores the clinical need to investigate all patients with persistent musculoskeletal symptoms for hypophosphatemia. A systematic approach is of pivotal importance because early recognition and treatment of the metabolic abnormality can prevent deleterious effects of osteomalacia on the skeleton. Twit Text FOAVip Identifying the culprit lesion in tumor induced hypophosphatemia, the solution of a clinical enigma ????Endocrine http://www.kidney.de/pget.php?&tw=1&pmid=27709474 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27709474 #FOAvip English Wikipedia <ref>{{Cite pmid|27709474 }}</ref> Identifying the culprit lesion in tumor induced hypophosphatemia, the solution of a clinical enigma #MMPMID27709474 Slot-Steenks MM ; Hamdy NA ; van de Sande MA ; Vriens D ; Cleven AH ; Appelman-Dijkstra NM Endocrine 2016[Dec]; 54 (3 ): 642-647 PMID27709474 show ga Tumor-induced osteomalacia is a rare acquired metabolic bone disorder characterized by isolated renal phosphate wasting due to abnormal tumor production of fibroblast growth factor 23. We report the case of a 59 year old woman referred to our department with a long history of progressive diffuse muscle weakness and pain, generalized bone pains and multiple insufficiency fractures of heels, ankles and hips due to a hypophosphatemic osteomalacia. A fibroblast growth factor 23-producing phosphaturic mesenchymal tumor localized in the left quadriceps femoris muscle was identified 7 years after onset of symptoms. Excision of the tumor resulted in normalization of serum phosphate and fibroblast growth factor 23 levels and in complete resolution of the clinical picture with disappearance of all musculoskeletal symptoms. This case illustrates the diagnostic difficulties in establishing a diagnosis tumor-induced osteomalacia and in identifying the responsible tumor. Our case underscores the clinical need to investigate all patients with persistent musculoskeletal symptoms for hypophosphatemia. A systematic approach is of pivotal importance because early recognition and treatment of the metabolic abnormality can prevent deleterious effects of osteomalacia on the skeleton. |Female [MESH] |Fibroblast Growth Factor-23 [MESH] |Fibroblast Growth Factors/*metabolism [MESH] |Humans [MESH] |Hypophosphatemia/diagnostic imaging/*etiology [MESH] |Middle Aged [MESH] |Muscle Neoplasms/*diagnostic imaging/metabolism [MESH] |Neoplasms, Connective Tissue/diagnostic imaging/*etiology [MESH] |Osteomalacia [MESH]Identifying the culprit lesion in tumor induced hypophosphatemia, the (epmc).pdf DeepDyve Pubget Overpricing