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10.1007/s00134-016-4536-8 http://scihub22266oqcxt.onion/10.1007/s00134-016-4536-8 C5106498!5106498!27647331     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Intensive+Care+Med 2016 ; 42 (12): 1922-34 Nephropedia Template TP {{tp|p=27647331|t=2016. Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysis |pdf=|usr=}}{{27647331}} gab.com Text Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysis JO: Intensive Care Med http://www.kidney.de/pget.php?&tw=1&pmid=27647331 #FOAvip Purpose: Veno-arterial extracorporeal life support (ECLS) is increasingly used in patients during cardiac arrest and cardiogenic shock, to support both cardiac and pulmonary function. We performed a systematic review and meta-analysis of cohort studies comparing mortality in patients treated with and without ECLS support in the setting of refractory cardiac arrest and cardiogenic shock complicating acute myocardial infarction. Methods: We systematically searched MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials and the publisher subset of PubMed updated to December 2015. Thirteen studies were included of which nine included cardiac arrest patients (n = 3098) and four included patients with cardiogenic shock after acute myocardial infarction (n = 235). Data were pooled by a Mantel-Haenzel random effects model and heterogeneity was examined by the I2 statistic. Results: In cardiac arrest, the use of ECLS was associated with an absolute increase of 30 days survival of 13 % compared with patients in which ECLS was not used [95 % CI 6?20 %; p < 0.001; number needed to treat (NNT) 7.7] and a higher rate of favourable neurological outcome at 30 days (absolute risk difference 14 %; 95 % CI 7?20 %; p < 0.0001; NNT 7.1). Propensity matched analysis, including 5 studies and 438 patients (219 in both groups), showed similar results. In cardiogenic shock, ECLS showed a 33 % higher 30-day survival compared with IABP (95 % CI, 14?52 %; p < 0.001; NNT 13) but no difference when compared with TandemHeart/Impella (?3 %; 95 % CI ?21 to 14 %; p = 0.70; NNH 33). Conclusions: In cardiac arrest, the use of ECLS was associated with an increased survival rate as well as an increase in favourable neurological outcome. In the setting of cardiogenic shock there was an increased survival with ECLS compared with IABP. Electronic supplementary material: The online version of this article (doi:10.1007/s00134-016-4536-8) contains supplementary material, which is available to authorized users. Twit Text FOAVip Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysis ????Intensive Care Med http://www.kidney.de/pget.php?&tw=1&pmid=27647331 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27647331 #FOAvip English Wikipedia <ref>{{Cite pmid|27647331}}</ref> Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysis #MMPMID27647331 Ouweneel DM; Schotborgh JV; Limpens J; Sjauw KD; Engström AE; Lagrand WK; Cherpanath TGV; Driessen AHG; de Mol BAJM; Henriques JPS Intensive Care Med 2016[]; 42 (12): 1922-34 PMID27647331show ga Purpose: Veno-arterial extracorporeal life support (ECLS) is increasingly used in patients during cardiac arrest and cardiogenic shock, to support both cardiac and pulmonary function. We performed a systematic review and meta-analysis of cohort studies comparing mortality in patients treated with and without ECLS support in the setting of refractory cardiac arrest and cardiogenic shock complicating acute myocardial infarction. Methods: We systematically searched MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials and the publisher subset of PubMed updated to December 2015. Thirteen studies were included of which nine included cardiac arrest patients (n = 3098) and four included patients with cardiogenic shock after acute myocardial infarction (n = 235). Data were pooled by a Mantel-Haenzel random effects model and heterogeneity was examined by the I2 statistic. Results: In cardiac arrest, the use of ECLS was associated with an absolute increase of 30 days survival of 13 % compared with patients in which ECLS was not used [95 % CI 6?20 %; p < 0.001; number needed to treat (NNT) 7.7] and a higher rate of favourable neurological outcome at 30 days (absolute risk difference 14 %; 95 % CI 7?20 %; p < 0.0001; NNT 7.1). Propensity matched analysis, including 5 studies and 438 patients (219 in both groups), showed similar results. In cardiogenic shock, ECLS showed a 33 % higher 30-day survival compared with IABP (95 % CI, 14?52 %; p < 0.001; NNT 13) but no difference when compared with TandemHeart/Impella (?3 %; 95 % CI ?21 to 14 %; p = 0.70; NNH 33). Conclusions: In cardiac arrest, the use of ECLS was associated with an increased survival rate as well as an increase in favourable neurological outcome. In the setting of cardiogenic shock there was an increased survival with ECLS compared with IABP. Electronic supplementary material: The online version of this article (doi:10.1007/s00134-016-4536-8) contains supplementary material, which is available to authorized users. äExtracorporeal life support during cardiac arrest and cardiogenic shoc(epmc).pdf DeepDyve Pubget Overpricing