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10.1080/15384101.2016.1231280 http://scihub22266oqcxt.onion/10.1080/15384101.2016.1231280 C5105929!5105929 !27625181     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27625181 &cmd=llinks): Failed to open stream: HTTP request failed! 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Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding |pdf=|usr=}}{{27625181 }} gab.com Text Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding JO: Cell Cycle http://www.kidney.de/pget.php?&tw=1&pmid=27625181 #FOAvip In order to achieve accurate chromosome segregation, eukaryotic cells undergo a dramatic change in morphology to obtain a spherical shape during mitosis. Interphase cells communicate directly with each other by exchanging ions and small molecules via gap junctions, which have important roles in controlling cell growth and differentiation. As cells round up during mitosis, the gap junctional communication between mitotic cells and adjacent interphase cells ceases. Whether mitotic cells use alternative mechanisms for mediating direct cell-cell communication during rounding is currently unknown. Here, we have studied the mechanisms involved in the remodeling of gap junctions during mitosis. We further demonstrate that mitotic cells are able to form actin-based plasma membrane bridges with adjacent cells during rounding. These structures, termed "mitotic nanotubes," were found to be involved in mediating the transport of cytoplasm, including Rab11-positive vesicles, between mitotic cells and adjacent cells. Moreover, a subpool of the gap-junction channel protein connexin43 localized in these intercellular bridges during mitosis. Collectively, the data provide new insights into the mechanisms involved in the remodeling of gap junctions during mitosis and identify actin-based plasma membrane bridges as a novel means of communication between mitotic cells and adjacent cells during rounding. Twit Text FOAVip Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding ????Cell Cycle http://www.kidney.de/pget.php?&tw=1&pmid=27625181 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27625181 #FOAvip English Wikipedia <ref>{{Cite pmid|27625181 }}</ref> Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding #MMPMID27625181 Fykerud TA ; Knudsen LM ; Totland MZ ; Sørensen V ; Dahal-Koirala S ; Lothe RA ; Brech A ; Leithe E Cell Cycle 2016[Nov]; 15 (21 ): 2943-2957 PMID27625181 show ga In order to achieve accurate chromosome segregation, eukaryotic cells undergo a dramatic change in morphology to obtain a spherical shape during mitosis. Interphase cells communicate directly with each other by exchanging ions and small molecules via gap junctions, which have important roles in controlling cell growth and differentiation. As cells round up during mitosis, the gap junctional communication between mitotic cells and adjacent interphase cells ceases. Whether mitotic cells use alternative mechanisms for mediating direct cell-cell communication during rounding is currently unknown. Here, we have studied the mechanisms involved in the remodeling of gap junctions during mitosis. We further demonstrate that mitotic cells are able to form actin-based plasma membrane bridges with adjacent cells during rounding. These structures, termed "mitotic nanotubes," were found to be involved in mediating the transport of cytoplasm, including Rab11-positive vesicles, between mitotic cells and adjacent cells. Moreover, a subpool of the gap-junction channel protein connexin43 localized in these intercellular bridges during mitosis. Collectively, the data provide new insights into the mechanisms involved in the remodeling of gap junctions during mitosis and identify actin-based plasma membrane bridges as a novel means of communication between mitotic cells and adjacent cells during rounding. |*Cell Communication [MESH] |*Cell Shape [MESH] |*Mitosis [MESH] |Actins/*metabolism [MESH] |Animals [MESH] |Cell Membrane/metabolism [MESH] |Connexin 43/metabolism [MESH] |Cytoplasmic Vesicles/metabolism [MESH] |Cytoskeletal Proteins/metabolism [MESH] |Endocytosis [MESH] |HeLa Cells [MESH] |Humans [MESH] |Models, Biological [MESH] |Nanotubes [MESH] |Rats [MESH] |Ubiquitin-Protein Ligases/metabolism [MESH]Mitotic cells form actin-based bridges with adjacent cells to provide (epmc).pdf DeepDyve Pubget Overpricing