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10.1074/jbc.M116.756155 http://scihub22266oqcxt.onion/10.1074/jbc.M116.756155 C5104929!5104929!27645994     free     free     free       J+Biol+Chem 2016 ; 291 (46): 24036-40 Nephropedia Template TP {{tp|p=27645994|t=2016. Selenoprotein Gene Nomenclature* |pdf=|usr=}}{{27645994}} gab.com Text Selenoprotein Gene Nomenclature* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=27645994 #FOAvip The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis. Selenoprotein enzymes with known functions are designated according to these functions: TXNRD1, TXNRD2, and TXNRD3 (thioredoxin reductases), GPX1, GPX2, GPX3, GPX4, and GPX6 (glutathione peroxidases), DIO1, DIO2, and DIO3 (iodothyronine deiodinases), MSRB1 (methionine sulfoxide reductase B1), and SEPHS2 (selenophosphate synthetase 2). Selenoproteins without known functions have traditionally been denoted by SEL or SEP symbols. However, these symbols are sometimes ambiguous and conflict with the approved nomenclature for several other genes. Therefore, there is a need to implement a rational and coherent nomenclature system for selenoprotein-encoding genes. Our solution is to use the root symbol SELENO followed by a letter. This nomenclature applies to SELENOF (selenoprotein F, the 15-kDa selenoprotein, SEP15), SELENOH (selenoprotein H, SELH, C11orf31), SELENOI (selenoprotein I, SELI, EPT1), SELENOK (selenoprotein K, SELK), SELENOM (selenoprotein M, SELM), SELENON (selenoprotein N, SEPN1, SELN), SELENOO (selenoprotein O, SELO), SELENOP (selenoprotein P, SeP, SEPP1, SELP), SELENOS (selenoprotein S, SELS, SEPS1, VIMP), SELENOT (selenoprotein T, SELT), SELENOV (selenoprotein V, SELV), and SELENOW (selenoprotein W, SELW, SEPW1). This system, approved by the HUGO Gene Nomenclature Committee, also resolves conflicting, missing, and ambiguous designations for selenoprotein genes and is applicable to selenoproteins across vertebrates. Twit Text FOAVip Selenoprotein Gene Nomenclature* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=27645994 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27645994 #FOAvip English Wikipedia <ref>{{Cite pmid|27645994}}</ref> Selenoprotein Gene Nomenclature* #MMPMID27645994 Gladyshev VN; Arnér ES; Berry MJ; Brigelius-Flohé R; Bruford EA; Burk RF; Carlson BA; Castellano S; Chavatte L; Conrad M; Copeland PR; Diamond AM; Driscoll DM; Ferreiro A; Flohé L; Green FR; Guigó R; Handy DE; Hatfield DL; Hesketh J; Hoffmann PR; Holmgren A; Hondal RJ; Howard MT; Huang K; Kim HY; Kim IY; Köhrle J; Krol A; Kryukov GV; Lee BJ; Lee BC; Lei XG; Liu Q; Lescure A; Lobanov AV; Loscalzo J; Maiorino M; Mariotti M; Sandeep Prabhu K; Rayman MP; Rozovsky S; Salinas G; Schmidt EE; Schomburg L; Schweizer U; Simonovi? M; Sunde RA; Tsuji PA; Tweedie S; Ursini F; Whanger PD; Zhang Y J Biol Chem 2016[Nov]; 291 (46): 24036-40 PMID27645994show ga The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis. Selenoprotein enzymes with known functions are designated according to these functions: TXNRD1, TXNRD2, and TXNRD3 (thioredoxin reductases), GPX1, GPX2, GPX3, GPX4, and GPX6 (glutathione peroxidases), DIO1, DIO2, and DIO3 (iodothyronine deiodinases), MSRB1 (methionine sulfoxide reductase B1), and SEPHS2 (selenophosphate synthetase 2). Selenoproteins without known functions have traditionally been denoted by SEL or SEP symbols. However, these symbols are sometimes ambiguous and conflict with the approved nomenclature for several other genes. Therefore, there is a need to implement a rational and coherent nomenclature system for selenoprotein-encoding genes. Our solution is to use the root symbol SELENO followed by a letter. This nomenclature applies to SELENOF (selenoprotein F, the 15-kDa selenoprotein, SEP15), SELENOH (selenoprotein H, SELH, C11orf31), SELENOI (selenoprotein I, SELI, EPT1), SELENOK (selenoprotein K, SELK), SELENOM (selenoprotein M, SELM), SELENON (selenoprotein N, SEPN1, SELN), SELENOO (selenoprotein O, SELO), SELENOP (selenoprotein P, SeP, SEPP1, SELP), SELENOS (selenoprotein S, SELS, SEPS1, VIMP), SELENOT (selenoprotein T, SELT), SELENOV (selenoprotein V, SELV), and SELENOW (selenoprotein W, SELW, SEPW1). This system, approved by the HUGO Gene Nomenclature Committee, also resolves conflicting, missing, and ambiguous designations for selenoprotein genes and is applicable to selenoproteins across vertebrates. äSelenoprotein Gene Nomenclature* (epmc).pdf DeepDyve Pubget Overpricing