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10.1186/s12944-016-0360-y

http://scihub22266oqcxt.onion/10.1186/s12944-016-0360-y
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C5101799!5101799!27825356
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suck abstract from ncbi


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pmid27825356      Lipids+Health+Dis 2016 ; 15 (ä): ä
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  • The association between oxidized low-density lipoprotein antibodies and hematological diseases #MMPMID27825356
  • Li H; Li Dq; Li Xx; Wang Lq
  • Lipids Health Dis 2016[]; 15 (ä): ä PMID27825356show ga
  • Background: The aim of the study is to compare the profiles of antibodies (IgM and IgG) against oxidized low-density lipoprotein (oxLDL) of hematological diseases. Methods: The serum antibodies of oxLDL-IgM and oxLDL-IgG for 446 cases with hematological diseases and 90 patients with primary hypertension and 90 healthy controls were measured by enzyme-linked immunosorbent assay (ELISA) in a cross-section survey. The association of serum oxLDL-LgM and oxLDL-IgG with hematological diseases was analyzed by multiple linear regression model. Results: Comparing with the hypertension or normal groups, the levels of TCH, TG, LDL-c, HDL-c, oxLDL, and oxLDL-IgG were lower and the levels of ADP and oxLDL-IgM were higher in the hematological diseases group. The levels of oxLDL-IgG antibodies titer were different among hematological diseases group. The results of correlation and multiple regression analysis showed that the seven hematological disease subgroups were positively related to the oxLDL-IgM antibody titer but negatively related to the oxLDL-IgG antibody titer, having been adjusted for potential confounding factors such as age, SBP, DBP, BMI, TCH, TG, ADP, oxLDL, HDL-c, LDL-C. Conclusions: Here we show that oxLDL-IgG antibodies titer were lower and of oxLDL-IgM titer were higher than hypertension and healthy individuals. Also oxLDL-IgG titer were different among hematological diseases group.
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