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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Occup+Med+Toxicol
2016 ; 11
(ä): 49
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Alternative drugs go global: possible lead and/ or mercury intoxication from
imported natural health products and a need for scientifically evaluated
poisoning monitoring from environmental exposures
#MMPMID27833648
Budnik LT
; Baur X
; Harth V
; Hahn A
J Occup Med Toxicol
2016[]; 11
(ä): 49
PMID27833648
show ga
BACKGROUND: With increases in globalization, cultural remedies from Chinese,
Ayurvedic, Arab and other traditions have become more available to international
consumers, offering unfamiliar "Natural Health Products" (NHP), used as
alternative medicine or supplementary medicine. Contamination with toxic
ingredients including lead, mercury, arsenic, and other toxic elements has been
documented in several of these products from various parts of the globe,
particularly from some parts of Asia and the Orient. FINDINGS: We have been
following this development in the last 6 years and have analyzed n?=?20 such
products (60 analyses) from patients with intoxication symptoms in a pilot study,
showing alarming high concentrations of mercury and/or lead (the first one in
"therapeutic" doses). 82 % of the studied NHP contained lead concentrations above
the EU limit for dietary supplements. 62 % of the samples exceeded the limit
values for mercury. Elevated blood lead and mercury levels in patients along with
clinical intoxication symptoms corroborate the causal assumption of intoxication
(s). We present one detailed clinical case report of severe lead and mercury
intoxications and give an overview about blood concentration related symptoms and
signs of n?=?41 case reports of mercury intoxications of the German monitoring
BfR-DocCenter. CONCLUSIONS: For NHP there is evidence on a distinct toxicological
risk with alarming low awareness for a possible intoxication which prevents
potentially life-saving diagnostic steps in affected cases. In many cases
patients do not communicate the events to their physicians or the local health
authority so that case reports (e.g. the BfR-DocCentre) are missing. Thus, there
is an urgent need to raise awareness and to initiate more suitable monitory
systems (e.g. National Monitoring of Poisonings) and control practice protecting
the public.