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10.1155/2016/5128720 http://scihub22266oqcxt.onion/10.1155/2016/5128720 C5099469!5099469 !27847402     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27847402 &cmd=llinks): Failed to open stream: HTTP request failed! 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Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with Breast Tumors of Different Histological Types and Grades |pdf=|usr=}}{{27847402 }} gab.com Text Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with Breast Tumors of Different Histological Types and Grades JO: Dis Markers http://www.kidney.de/pget.php?&tw=1&pmid=27847402 #FOAvip Purpose. To investigate a frequency of antibody response to SEREX-identified medullary breast carcinoma autoantigens ZRF1 and KRR1 in sera of breast cancer patients taking into account clinical and molecular characteristics of tumors for opening of new perspectives in creation of minimally invasive immunological tests for cancer diagnostics. Methods. Enzyme-linked immunosorbent assay and bioinformatics analysis. Results. Increased frequency of antibody response was found in sera of breast cancer patients to ZRF and KRR1 antigens. The antibody response to these antigens was higher in sera of patients with invasive ductal carcinoma than in sera of patients with other histological types of breast tumors. Moreover, more frequent antibody response to ZRF antigen was found in sera of patients with less aggressive tumors. The sequence analysis of ZRF1 antigen SEREX clones obtained from cDNA libraries of different tumors demonstrates that they encode different protein isoforms. Conclusion. Tumor-associated antigens KRR1 and ZRF1 and their cognate autoantibodies could be considered as potential molecular markers of breast cancer which need to be further investigated. Twit Text FOAVip Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with Breast Tumors of Different Histological Types and Grades ????Dis Markers http://www.kidney.de/pget.php?&tw=1&pmid=27847402 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27847402 #FOAvip English Wikipedia <ref>{{Cite pmid|27847402 }}</ref> Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with Breast Tumors of Different Histological Types and Grades #MMPMID27847402 Dyachenko L ; Havrysh K ; Lytovchenko A ; Dosenko I ; Antoniuk S ; Filonenko V ; Kiyamova R Dis Markers 2016[]; 2016 (ä): 5128720 PMID27847402 show ga Purpose. To investigate a frequency of antibody response to SEREX-identified medullary breast carcinoma autoantigens ZRF1 and KRR1 in sera of breast cancer patients taking into account clinical and molecular characteristics of tumors for opening of new perspectives in creation of minimally invasive immunological tests for cancer diagnostics. Methods. Enzyme-linked immunosorbent assay and bioinformatics analysis. Results. Increased frequency of antibody response was found in sera of breast cancer patients to ZRF and KRR1 antigens. The antibody response to these antigens was higher in sera of patients with invasive ductal carcinoma than in sera of patients with other histological types of breast tumors. Moreover, more frequent antibody response to ZRF antigen was found in sera of patients with less aggressive tumors. The sequence analysis of ZRF1 antigen SEREX clones obtained from cDNA libraries of different tumors demonstrates that they encode different protein isoforms. Conclusion. Tumor-associated antigens KRR1 and ZRF1 and their cognate autoantibodies could be considered as potential molecular markers of breast cancer which need to be further investigated. |Adolescent [MESH] |Adult [MESH] |Aged [MESH] |Aged, 80 and over [MESH] |Antigens, Neoplasm/*blood/genetics/immunology [MESH] |Autoantibodies/*blood [MESH] |Base Sequence [MESH] |Biomarkers, Tumor/*blood/immunology [MESH] |Breast Neoplasms/blood/*immunology/pathology [MESH] |Carcinoma, Ductal, Breast/blood/immunology/pathology [MESH] |Carcinoma, Lobular/blood/immunology/pathology [MESH] |Carcinoma, Medullary/blood/immunology/pathology [MESH] |Case-Control Studies [MESH] |DNA-Binding Proteins/*blood/genetics/immunology [MESH] |Enzyme-Linked Immunosorbent Assay [MESH] |Female [MESH] |Follow-Up Studies [MESH] |Gene Library [MESH] |Humans [MESH] |Middle Aged [MESH] |Molecular Chaperones [MESH] |Neoplasm Grading [MESH] |Neoplasm Staging [MESH] |Nuclear Pore Complex Proteins/blood/genetics/immunology [MESH] |Oncogene Proteins/*blood/genetics/immunology [MESH] |Prognosis [MESH] |RNA-Binding Proteins/blood/genetics/immunology [MESH]Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with(epmc).pdf DeepDyve Pubget Overpricing