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10.1186/s13054-016-1530-z http://scihub22266oqcxt.onion/10.1186/s13054-016-1530-z C5097407!5097407!27814743     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 300.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 300.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 300.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Crit+Care 2016 ; 20 (ä): ä Nephropedia Template TP {{tp|p=27814743|t=2016. Prehospital fibrinolysis versus primary percutaneous coronary intervention in ST-elevation myocardial infarction: a systematic review and meta-analysis of randomized controlled trials |pdf=|usr=}}{{27814743}} gab.com Text Prehospital fibrinolysis versus primary percutaneous coronary intervention in ST-elevation myocardial infarction: a systematic review and meta-analysis of randomized controlled trials JO: Crit Care http://www.kidney.de/pget.php?&tw=1&pmid=27814743 #FOAvip Background: Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion strategy in patients with ST-elevation myocardial infarction (STEMI), but its benefit over prehospital fibrinolysis (FL) is not clear. Methods: We performed a systematic review and meta-analysis of randomized controlled trials in which outcomes of patients with STEMI managed with FL early in the prehospital setting versus PPCI were compared. Results: Compared with PPCI, FL was consistently associated with similar rates of short-term (30?90 days) death (relative risk [RR] 0.94, 95 % CI 0.67?1.31) and cardiovascular death (RR 0.95, 95 % CI 0.64?1.4), a decreased risk of cardiogenic shock (RR 0.67, 95 % CI 0.48?0.95), and an increased risk of any stroke (RR 3.57, 95 % CI 1.39?9.17) and hemorrhagic stroke (RR 4.37, 95 % CI 1.25?15.26). FL was also associated with similar rates of 1-year mortality (RR 1.01, 95 % CI 0.75?1.34) and major bleeding (RR 1.31, 95 % CI 0.96?1.78) in comparison with PPCI, but with a notable level (I2 index 30.5 % and 59.8 %) of heterogeneity among studies. Conclusions: Our study suggests that, compared with PPCI, FL performed in the early prehospital setting is associated with similar mortality rates, lower rates of cardiogenic shock, and higher rates of stroke in patients with STEMI. Although the number of studies comparing the two strategies is relatively low, our results support prehospital FL and transfer to hub percutaneous coronary intervention (PCI) centers as a valid alternative to PPCI, allowing potential limitation of resources allocated to developing proximity 24/7 PCI facilities. Electronic supplementary material: The online version of this article (doi:10.1186/s13054-016-1530-z) contains supplementary material, which is available to authorized users. Twit Text FOAVip Prehospital fibrinolysis versus primary percutaneous coronary intervention in ST-elevation myocardial infarction: a systematic review and meta-analysis of randomized controlled trials ????Crit Care http://www.kidney.de/pget.php?&tw=1&pmid=27814743 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27814743 #FOAvip English Wikipedia <ref>{{Cite pmid|27814743}}</ref> Prehospital fibrinolysis versus primary percutaneous coronary intervention in ST-elevation myocardial infarction: a systematic review and meta-analysis of randomized controlled trials #MMPMID27814743 Roule V; Ardouin P; Blanchart K; Lemaitre A; Wain-Hobson J; Legallois D; Alexandre J; Sabatier R; Milliez P; Beygui F Crit Care 2016[]; 20 (ä): ä PMID27814743show ga Background: Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion strategy in patients with ST-elevation myocardial infarction (STEMI), but its benefit over prehospital fibrinolysis (FL) is not clear. Methods: We performed a systematic review and meta-analysis of randomized controlled trials in which outcomes of patients with STEMI managed with FL early in the prehospital setting versus PPCI were compared. Results: Compared with PPCI, FL was consistently associated with similar rates of short-term (30?90 days) death (relative risk [RR] 0.94, 95 % CI 0.67?1.31) and cardiovascular death (RR 0.95, 95 % CI 0.64?1.4), a decreased risk of cardiogenic shock (RR 0.67, 95 % CI 0.48?0.95), and an increased risk of any stroke (RR 3.57, 95 % CI 1.39?9.17) and hemorrhagic stroke (RR 4.37, 95 % CI 1.25?15.26). FL was also associated with similar rates of 1-year mortality (RR 1.01, 95 % CI 0.75?1.34) and major bleeding (RR 1.31, 95 % CI 0.96?1.78) in comparison with PPCI, but with a notable level (I2 index 30.5 % and 59.8 %) of heterogeneity among studies. Conclusions: Our study suggests that, compared with PPCI, FL performed in the early prehospital setting is associated with similar mortality rates, lower rates of cardiogenic shock, and higher rates of stroke in patients with STEMI. Although the number of studies comparing the two strategies is relatively low, our results support prehospital FL and transfer to hub percutaneous coronary intervention (PCI) centers as a valid alternative to PPCI, allowing potential limitation of resources allocated to developing proximity 24/7 PCI facilities. Electronic supplementary material: The online version of this article (doi:10.1186/s13054-016-1530-z) contains supplementary material, which is available to authorized users. äPrehospital fibrinolysis versus primary percutaneous coronary interven(epmc).pdf DeepDyve Pubget Overpricing