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10.1038/srep36455 http://scihub22266oqcxt.onion/10.1038/srep36455 C5095553!5095553 !27811984     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27811984 &cmd=llinks): Failed to open stream: HTTP request failed! 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Presence of Streptococcus mutans strains harbouring the cnm gene correlates with dental caries status and IgA nephropathy conditions |pdf=|usr=}}{{27811984 }} gab.com Text Presence of Streptococcus mutans strains harbouring the cnm gene correlates with dental caries status and IgA nephropathy conditions JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27811984 #FOAvip Streptococcus mutans is a major pathogen of human dental caries. Strains harbouring the cnm gene, which encodes Cnm, a collagen-binding protein, contribute to the development of several systemic diseases. In this study, we analysed S. mutans strains isolated from the oral cavity of immunoglobulin (Ig)A nephropathy (IgAN) patients to determine potential relationships between cnm and caries status as well as IgAN conditions. Saliva specimens were collected from 109 IgAN patients and the cnm status of isolated S. mutans strains was determined using PCR. In addition, the dental caries status (decayed, missing or filled teeth [DMFT] index) in patients who agreed to dental consultation (n?=?49) was evaluated. The DMFT index and urinary protein levels in the cnm-positive group were significantly higher than those in the cnm-negative group (p?<?0.05). Moreover, the urinary protein levels in the high DMFT (?15) group were significantly higher than those in the low DMFT (<15) group (p?<?0.05). Our results show that isolation of cnm-positive S. mutans strains from the oral cavity may be associated with urinary protein levels in IgAN patients, especially those with a high dental caries status. Twit Text FOAVip Presence of Streptococcus mutans strains harbouring the cnm gene correlates with dental caries status and IgA nephropathy conditions ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27811984 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27811984 #FOAvip English Wikipedia <ref>{{Cite pmid|27811984 }}</ref> Presence of Streptococcus mutans strains harbouring the cnm gene correlates with dental caries status and IgA nephropathy conditions #MMPMID27811984 Misaki T ; Naka S ; Hatakeyama R ; Fukunaga A ; Nomura R ; Isozaki T ; Nakano K Sci Rep 2016[Nov]; 6 (ä): 36455 PMID27811984 show ga Streptococcus mutans is a major pathogen of human dental caries. Strains harbouring the cnm gene, which encodes Cnm, a collagen-binding protein, contribute to the development of several systemic diseases. In this study, we analysed S. mutans strains isolated from the oral cavity of immunoglobulin (Ig)A nephropathy (IgAN) patients to determine potential relationships between cnm and caries status as well as IgAN conditions. Saliva specimens were collected from 109 IgAN patients and the cnm status of isolated S. mutans strains was determined using PCR. In addition, the dental caries status (decayed, missing or filled teeth [DMFT] index) in patients who agreed to dental consultation (n?=?49) was evaluated. The DMFT index and urinary protein levels in the cnm-positive group were significantly higher than those in the cnm-negative group (p? |Adhesins, Bacterial/*genetics/metabolism [MESH] |Adult [MESH] |Blood Pressure [MESH] |Carrier Proteins/*genetics/metabolism [MESH] |Case-Control Studies [MESH] |Creatinine/blood [MESH] |Dental Caries/complications/*pathology [MESH] |Female [MESH] |Glomerular Filtration Rate [MESH] |Glomerulonephritis, IGA/complications/*pathology [MESH] |Humans [MESH] |Male [MESH] |Middle Aged [MESH] |Polymerase Chain Reaction [MESH] |Proteinuria/complications/pathology [MESH] |Saliva/microbiology [MESH]Presence of Streptococcus mutans strains harbouring the cnm gene corre(epmc).pdf DeepDyve Pubget Overpricing