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10.1038/srep36048 http://scihub22266oqcxt.onion/10.1038/srep36048 C5093735!5093735 !27808112     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27808112 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Sci+Rep 2016 ; 6 (ä): 36048 Nephropedia Template TP {{tp|p=27808112 |t=2016. Fish gut-liver immunity during homeostasis or inflammation revealed by integrative transcriptome and proteome studies |pdf=|usr=}}{{27808112 }} gab.com Text Fish gut-liver immunity during homeostasis or inflammation revealed by integrative transcriptome and proteome studies JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27808112 #FOAvip The gut-associated lymphoid tissue, connected with liver via bile and blood, constructs a local immune environment of both defense and tolerance. The gut-liver immunity has been well-studied in mammals, yet in fish remains largely unknown, even though enteritis as well as liver and gallbladder syndrome emerged as a limitation in aquaculture. In this study, we performed integrative bioinformatic analysis for both transcriptomic (gut and liver) and proteomic (intestinal mucus and bile) data, in both healthy and infected tilapias. We found more categories of immune transcripts in gut than liver, as well as more adaptive immune in gut meanwhile more innate in liver. Interestingly reduced differential immune transcripts between gut and liver upon inflammation were also revealed. In addition, more immune proteins in bile than intestinal mucus were identified. And bile probably providing immune effectors to intestinal mucus upon inflammation was deduced. Specifically, many key immune transcripts in gut or liver as well as key immune proteins in mucus or bile were demonstrated. Accordingly, we proposed a hypothesized profile of fish gut-liver immunity, during either homeostasis or inflammation. Current data suggested that fish gut and liver may collaborate immunologically while keep homeostasis using own strategies, including potential unique mechanisms. Twit Text FOAVip Fish gut-liver immunity during homeostasis or inflammation revealed by integrative transcriptome and proteome studies ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27808112 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27808112 #FOAvip English Wikipedia <ref>{{Cite pmid|27808112 }}</ref> Fish gut-liver immunity during homeostasis or inflammation revealed by integrative transcriptome and proteome studies #MMPMID27808112 Wu N ; Song YL ; Wang B ; Zhang XY ; Zhang XJ ; Wang YL ; Cheng YY ; Chen DD ; Xia XQ ; Lu YS ; Zhang YA Sci Rep 2016[Nov]; 6 (ä): 36048 PMID27808112 show ga The gut-associated lymphoid tissue, connected with liver via bile and blood, constructs a local immune environment of both defense and tolerance. The gut-liver immunity has been well-studied in mammals, yet in fish remains largely unknown, even though enteritis as well as liver and gallbladder syndrome emerged as a limitation in aquaculture. In this study, we performed integrative bioinformatic analysis for both transcriptomic (gut and liver) and proteomic (intestinal mucus and bile) data, in both healthy and infected tilapias. We found more categories of immune transcripts in gut than liver, as well as more adaptive immune in gut meanwhile more innate in liver. Interestingly reduced differential immune transcripts between gut and liver upon inflammation were also revealed. In addition, more immune proteins in bile than intestinal mucus were identified. And bile probably providing immune effectors to intestinal mucus upon inflammation was deduced. Specifically, many key immune transcripts in gut or liver as well as key immune proteins in mucus or bile were demonstrated. Accordingly, we proposed a hypothesized profile of fish gut-liver immunity, during either homeostasis or inflammation. Current data suggested that fish gut and liver may collaborate immunologically while keep homeostasis using own strategies, including potential unique mechanisms. |*Homeostasis [MESH] |*Immunity, Mucosal [MESH] |Animals [MESH] |Bile/metabolism [MESH] |Fishes/genetics/*immunology [MESH] |Gastrointestinal Tract/*immunology [MESH] |Gene Expression Regulation [MESH] |Gene Library [MESH] |Gene Ontology [MESH] |Inflammation/*genetics/immunology/metabolism [MESH] |Liver/*immunology [MESH] |Mucus/metabolism [MESH] |Protein Domains [MESH] |Proteome/*metabolism [MESH] |RNA, Messenger/genetics/metabolism [MESH]Fish gut-liver immunity during homeostasis or inflammation revealed by(epmc).pdf DeepDyve Pubget Overpricing