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Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Cutan+Med+Surg 2014 ; 18 (5): 361 Nephropedia Template TP
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Pyoderma gangrenosum among patients with inflammatory bowel disease: a descriptive cohort study #MMPMID25277124
J Cutan Med Surg 2014[Oct]; 18 (5): 361 PMID25277124show ga
BACKGROUND: Pyoderma gangrenosum (PG) is a severe extra-intestinal manifestation of inflammatory bowel disease (IBD). OBJECTIVE: To better characterize PG features and management among an IBD cohort. METHODS: Subjects with PG were identified using a large database at a tertiary center. Patient demographics and clinical characteristics were summarized using descriptive statistics. RESULTS: 80 patients with an episode(s) of PG were identified, yielding an overall prevalence of 1.9%. Overall, 93% of patients with PG had some degree of colonic involvement. Thirty-one (39%) patients required hospitalization for PG. Underlying bowel disease was active at the time of PG episode(s) in 52 (65%) patients. PG location was variable, with the lower extremity being the most common. Most patients (71.3%) required multiple therapies to achieve PG healing. CONCLUSIONS: We have described one of the largest case series of PG among patients with IBD. The variety of treatment strategies used highlights the lack of clear guidelines in managing this complex group of patients.