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10.1016/j.celrep.2015.03.035 http://scihub22266oqcxt.onion/10.1016/j.celrep.2015.03.035 C5089169!5089169!25865893     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Rep 2015 ; 11 (3): 358-65 Nephropedia Template TP {{tp|p=25865893|t=2015. Entosis Allows Timely Elimination of the Luminal Epithelial Barrier for Embryo Implantation |pdf=|usr=}}{{25865893}} gab.com Text Entosis Allows Timely Elimination of the Luminal Epithelial Barrier for Embryo Implantation JO: Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=25865893 #FOAvip During implantation, uterine luminal epithelial (LE) cells first interact with the blastocyst trophectoderm. Within 30 hr after the initiation of attachment, LE cells surrounding the blastocyst in the implantation chamber (crypt) disappear, allowing trophoblast cells to make direct physical contact with the underneath stroma for successful implantation. The mechanism for the extraction of LE cells was thought to be mediated by apoptosis. Here, we show that LE cells in direct contact with the blastocyst are endocytosed by trophoblast cells by adopting the nonapoptotic cell-in-cell invasion process (entosis) in the absence of caspase 3 activation. Our in vivo observations were reinforced by the results of co-culture experiments with primary uterine epithelial cells with trophoblast stem cells or blastocysts showing internalization of epithelial cells by trophoblasts. We have identified entosis as a mechanism to remove LE cells by trophoblast cells in implantation, conferring a role for entosis in an important physiological process. Twit Text FOAVip Entosis Allows Timely Elimination of the Luminal Epithelial Barrier for Embryo Implantation ????Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=25865893 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25865893 #FOAvip English Wikipedia <ref>{{Cite pmid|25865893}}</ref> Entosis Allows Timely Elimination of the Luminal Epithelial Barrier for Embryo Implantation #MMPMID25865893 Li Y; Sun X; Dey SK Cell Rep 2015[Apr]; 11 (3): 358-65 PMID25865893show ga During implantation, uterine luminal epithelial (LE) cells first interact with the blastocyst trophectoderm. Within 30 hr after the initiation of attachment, LE cells surrounding the blastocyst in the implantation chamber (crypt) disappear, allowing trophoblast cells to make direct physical contact with the underneath stroma for successful implantation. The mechanism for the extraction of LE cells was thought to be mediated by apoptosis. Here, we show that LE cells in direct contact with the blastocyst are endocytosed by trophoblast cells by adopting the nonapoptotic cell-in-cell invasion process (entosis) in the absence of caspase 3 activation. Our in vivo observations were reinforced by the results of co-culture experiments with primary uterine epithelial cells with trophoblast stem cells or blastocysts showing internalization of epithelial cells by trophoblasts. We have identified entosis as a mechanism to remove LE cells by trophoblast cells in implantation, conferring a role for entosis in an important physiological process. äEntosis Allows Timely Elimination of the Luminal Epithelial Barrier fo(epmc).pdf DeepDyve Pubget Overpricing