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10.1101/gad.285726.116

http://scihub22266oqcxt.onion/10.1101/gad.285726.116
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C5088569!5088569!27798844
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suck abstract from ncbi


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pmid27798844      Genes+Dev 2016 ; 30 (19): 2213-25
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  • Post-transcriptional control of executioner caspases by RNA-binding proteins #MMPMID27798844
  • Subasic D; Stoeger T; Eisenring S; Matia-González AM; Imig J; Zheng X; Xiong L; Gisler P; Eberhard R; Holtackers R; Gerber AP; Pelkmans L; Hengartner MO
  • Genes Dev 2016[Oct]; 30 (19): 2213-25 PMID27798844show ga
  • In this study, Subasic et al. investigated the post-transcriptional control of caspases. The authors describe four conserved RNA-binding proteins (RBPs) that sequentially repress the CED-3 caspase in distinct regions of the C. elegans germline and identify seven RBPs that regulate human caspase-3 expression and/or activation, suggesting that translational inhibition of executioner caspases by RBPs might be a general strategy used widely across the animal kingdom to control apoptosis.
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