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2016 ; 55
(19
): 2831-2836
Nephropedia Template TP
Sugawara Y
; Honda K
; Katagiri D
; Nakamura M
; Kawakami T
; Nasu R
; Hayashi A
; Shintani Y
; Tojo A
; Noiri E
; Kurokawa M
; Fukayama M
; Nangaku M
Intern Med
2016[]; 55
(19
): 2831-2836
PMID27725544
show ga
The development of nephrotic syndrome (NS) after umbilical cord transplantation
(UBT) has been reported in only four cases to date. We herein report the case of
a 50-year-old woman who developed NS 94 days after UBT. She fell into oliguria
and required dialysis. A kidney biopsy revealed focal and segmental
glomerulosclerosis. Although glucocorticoid monotherapy did not improve her
condition, the addition of low-density lipoprotein (LDL) apheresis resulted in
remission of NS, a drastic improvement in her renal function, and withdrawal from
dialysis. To the best of our knowledge, this is the first report of
UBT-associated NS treated with LDL apheresis.