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10.2169/internalmedicine.55.7017

http://scihub22266oqcxt.onion/10.2169/internalmedicine.55.7017
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suck abstract from ncbi


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pmid27725544
      Intern+Med 2016 ; 55 (19 ): 2831-2836
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  • Umbilical Cord Blood Transplantation-associated Nephrotic Syndrome Successfully Treated by Low-density Lipoprotein Apheresis #MMPMID27725544
  • Sugawara Y ; Honda K ; Katagiri D ; Nakamura M ; Kawakami T ; Nasu R ; Hayashi A ; Shintani Y ; Tojo A ; Noiri E ; Kurokawa M ; Fukayama M ; Nangaku M
  • Intern Med 2016[]; 55 (19 ): 2831-2836 PMID27725544 show ga
  • The development of nephrotic syndrome (NS) after umbilical cord transplantation (UBT) has been reported in only four cases to date. We herein report the case of a 50-year-old woman who developed NS 94 days after UBT. She fell into oliguria and required dialysis. A kidney biopsy revealed focal and segmental glomerulosclerosis. Although glucocorticoid monotherapy did not improve her condition, the addition of low-density lipoprotein (LDL) apheresis resulted in remission of NS, a drastic improvement in her renal function, and withdrawal from dialysis. To the best of our knowledge, this is the first report of UBT-associated NS treated with LDL apheresis.
  • |Blood Component Removal/*methods [MESH]
  • |Cord Blood Stem Cell Transplantation/*adverse effects [MESH]
  • |Female [MESH]
  • |Glomerulosclerosis, Focal Segmental/complications/physiopathology [MESH]
  • |Humans [MESH]
  • |Lipoproteins, LDL/blood [MESH]
  • |Middle Aged [MESH]


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