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10.1007/s11886-016-0804-z http://scihub22266oqcxt.onion/10.1007/s11886-016-0804-z C5086478!5086478!27796860     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Cardiol+Rep 2016 ; 18 (12): ä Nephropedia Template TP {{tp|p=27796860|t=2016. Genetic Risk Factors for Ischemic and Hemorrhagic Stroke |pdf=|usr=}}{{27796860}} gab.com Text Genetic Risk Factors for Ischemic and Hemorrhagic Stroke JO: Curr Cardiol Rep http://www.kidney.de/pget.php?&tw=1&pmid=27796860 #FOAvip Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel therapeutic targets, and optimize the design of prevention strategies. A very small proportion of strokes are attributable to monogenic conditions, the vast majority being multifactorial, with multiple genetic and environmental risk factors of small effect size. Genome-wide association studies and large international consortia have been instrumental in finding genetic risk factors for stroke. While initial studies identified risk loci for specific stroke subtypes, more recent studies also revealed loci associated with all stroke and all ischemic stroke. Risk loci for ischemic stroke and its subtypes have been implicated in atrial fibrillation (PITX2 and ZFHX3), coronary artery disease (ABO, chr9p21, HDAC9, and ALDH2), blood pressure (ALDH2 and HDAC9), pericyte and smooth muscle cell development (FOXF2), coagulation (HABP2), carotid plaque formation (MMP12), and neuro-inflammation (TSPAN2). For hemorrhagic stroke, two loci (APOE and PMF1) have been identified. Twit Text FOAVip Genetic Risk Factors for Ischemic and Hemorrhagic Stroke ????Curr Cardiol Rep http://www.kidney.de/pget.php?&tw=1&pmid=27796860 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27796860 #FOAvip English Wikipedia <ref>{{Cite pmid|27796860}}</ref> Genetic Risk Factors for Ischemic and Hemorrhagic Stroke #MMPMID27796860 Chauhan G; Debette S Curr Cardiol Rep 2016[]; 18 (12): ä PMID27796860show ga Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel therapeutic targets, and optimize the design of prevention strategies. A very small proportion of strokes are attributable to monogenic conditions, the vast majority being multifactorial, with multiple genetic and environmental risk factors of small effect size. Genome-wide association studies and large international consortia have been instrumental in finding genetic risk factors for stroke. While initial studies identified risk loci for specific stroke subtypes, more recent studies also revealed loci associated with all stroke and all ischemic stroke. Risk loci for ischemic stroke and its subtypes have been implicated in atrial fibrillation (PITX2 and ZFHX3), coronary artery disease (ABO, chr9p21, HDAC9, and ALDH2), blood pressure (ALDH2 and HDAC9), pericyte and smooth muscle cell development (FOXF2), coagulation (HABP2), carotid plaque formation (MMP12), and neuro-inflammation (TSPAN2). For hemorrhagic stroke, two loci (APOE and PMF1) have been identified. äGenetic Risk Factors for Ischemic and Hemorrhagic Stroke (epmc).pdf DeepDyve Pubget Overpricing