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10.3390/ijms17101724 http://scihub22266oqcxt.onion/10.3390/ijms17101724 C5085755!5085755!27754413     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2016 ; 17 (10): ä Nephropedia Template TP {{tp|p=27754413|t=2016. UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer |pdf=|usr=}}{{27754413}} gab.com Text UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=27754413 #FOAvip The UBXD family is a diverse group of UBX (ubiquitin-regulatory X) domain-containing proteins in mammalian cells. Members of this family contain a UBX domain typically located at the carboxyl-terminal of the protein. In contrast to the UBX domain shared by all members of UBXD family, the amino-terminal domains are diverse and appear to carry out different roles in a subcellular localization-dependent manner. UBXD proteins are principally associated with the endoplasmic reticulum (ER), where they positively or negatively regulate the ER-associated degradation machinery (ERAD). The distinct protein interaction networks of UBXD proteins allow them to have specific functions independent of the ERAD pathway in a cell type- and tissue context-dependent manner. Recent reports have illustrated that a number of mammalian members of the UBXD family play critical roles in several proliferation and apoptosis pathways dysregulated in selected types of cancer. This review covers recent advances that elucidate the therapeutic potential of selected members of the UBXD family that can contribute to tumor growth. Twit Text FOAVip UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=27754413 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27754413 #FOAvip English Wikipedia <ref>{{Cite pmid|27754413}}</ref> UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer #MMPMID27754413 Rezvani K Int J Mol Sci 2016[Oct]; 17 (10): ä PMID27754413show ga The UBXD family is a diverse group of UBX (ubiquitin-regulatory X) domain-containing proteins in mammalian cells. Members of this family contain a UBX domain typically located at the carboxyl-terminal of the protein. In contrast to the UBX domain shared by all members of UBXD family, the amino-terminal domains are diverse and appear to carry out different roles in a subcellular localization-dependent manner. UBXD proteins are principally associated with the endoplasmic reticulum (ER), where they positively or negatively regulate the ER-associated degradation machinery (ERAD). The distinct protein interaction networks of UBXD proteins allow them to have specific functions independent of the ERAD pathway in a cell type- and tissue context-dependent manner. Recent reports have illustrated that a number of mammalian members of the UBXD family play critical roles in several proliferation and apoptosis pathways dysregulated in selected types of cancer. This review covers recent advances that elucidate the therapeutic potential of selected members of the UBXD family that can contribute to tumor growth. äUBXD Proteins: A Family of Proteins with Diverse Functions in Cancer (epmc).pdf DeepDyve Pubget Overpricing