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10.3390/ijms17101637 http://scihub22266oqcxt.onion/10.3390/ijms17101637 C5085670!5085670!27689992     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2016 ; 17 (10): ä Nephropedia Template TP {{tp|p=27689992|t=2016. Urine Levels of Defensin ?1 Reflect Kidney Injury in Leptospirosis Patients |pdf=|usr=}}{{27689992}} gab.com Text Urine Levels of Defensin 1 Reflect Kidney Injury in Leptospirosis Patients JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=27689992 #FOAvip Leptospirosis is a zoonotic disease whose severe forms are often accompanied by kidney dysfunction. In the present study, urinary markers were studied for potential prediction of disease severity. Urine samples from 135 patients with or without leptospirosis at San Lazaro Hospital, the Philippines, were analyzed. Urine levels of defensin ?1 (uDA1) were compared with those of neutrophil gelatinase-associated lipocalin (uNGAL) and N-acetyl-?-d-glucosidase (uNAG). Serum creatinine (Cr) was used as a marker of kidney injury. The levels of uDA1/Cr, uNGAL/Cr, and uNAG/Cr were positive in 46%, 90%, and 80% of leptospirosis patients, and 69%, 70%, and 70% of non-leptospirosis patients, respectively. In leptospirosis patients, the correlation of uDA1/Cr, uNGAL/Cr and uNAG/Cr levels with serum Cr were r = 0.3 (p < 0.01), r = 0.29 (p < 0.01), and r = 0.02 (p = 0.81), respectively. uDA1/Cr levels were correlated with uNGAL/Cr levels (r = 0.49, p < 0.01) and uNAG/Cr levels (r = 0.47, p < 0.0001) in leptospirosis patients. These findings suggest that uDA1, uNGAL, and uNAG were elevated in leptospirosis patients and reflected various types of kidney damage. uDA1 and uNGAL can be used to track kidney injury in leptospirosis patients because of their correlation with the serum Cr level. Twit Text FOAVip Urine Levels of Defensin 1 Reflect Kidney Injury in Leptospirosis Patients ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=27689992 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27689992 #FOAvip English Wikipedia <ref>{{Cite pmid|27689992}}</ref> Urine Levels of Defensin ?1 Reflect Kidney Injury in Leptospirosis Patients #MMPMID27689992 Chagan-Yasutan H; Chen Y; Lacuesta TL; Leano PSA; Iwasaki H; Hanan F; Taurustiati D; Ohmoto Y; Ashino Y; Saitoh H; Kiyomoto H; Suzuki Y; Telan FOE; Hattori T Int J Mol Sci 2016[Oct]; 17 (10): ä PMID27689992show ga Leptospirosis is a zoonotic disease whose severe forms are often accompanied by kidney dysfunction. In the present study, urinary markers were studied for potential prediction of disease severity. Urine samples from 135 patients with or without leptospirosis at San Lazaro Hospital, the Philippines, were analyzed. Urine levels of defensin ?1 (uDA1) were compared with those of neutrophil gelatinase-associated lipocalin (uNGAL) and N-acetyl-?-d-glucosidase (uNAG). Serum creatinine (Cr) was used as a marker of kidney injury. The levels of uDA1/Cr, uNGAL/Cr, and uNAG/Cr were positive in 46%, 90%, and 80% of leptospirosis patients, and 69%, 70%, and 70% of non-leptospirosis patients, respectively. In leptospirosis patients, the correlation of uDA1/Cr, uNGAL/Cr and uNAG/Cr levels with serum Cr were r = 0.3 (p < 0.01), r = 0.29 (p < 0.01), and r = 0.02 (p = 0.81), respectively. uDA1/Cr levels were correlated with uNGAL/Cr levels (r = 0.49, p < 0.01) and uNAG/Cr levels (r = 0.47, p < 0.0001) in leptospirosis patients. These findings suggest that uDA1, uNGAL, and uNAG were elevated in leptospirosis patients and reflected various types of kidney damage. uDA1 and uNGAL can be used to track kidney injury in leptospirosis patients because of their correlation with the serum Cr level. äUrine Levels of Defensin ?1 Reflect Kidney Injury in Leptospirosis Pat(epmc).pdf DeepDyve Pubget Overpricing