Nuclear calcium is required for human T cell activation #MMPMID27810914
Monaco S; Jahraus B; Samstag Y; Bading H
J Cell Biol 2016[Oct]; 215 (2): 231-43 PMID27810914show ga
Monaco et al. demonstrate that calcium signals in activated human T cells consist of a cytoplasmic and a nuclear component, which are both required for the immune response. Blockade of nuclear calcium signaling inhibits T cell activation and induces an anergy-like state.