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10.1016/j.diff.2016.07.001 http://scihub22266oqcxt.onion/10.1016/j.diff.2016.07.001 C5079826!5079826!27591095     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Differentiation 2016 ; 92 (3): 84-92 Nephropedia Template TP {{tp|p=27591095|t=2016. The Characteristics of Activated Portal Fibroblasts / Myofibroblasts in Liver Fibrosis |pdf=|usr=}}{{27591095}} gab.com Text The Characteristics of Activated Portal Fibroblasts / Myofibroblasts in Liver Fibrosis JO: Differentiation http://www.kidney.de/pget.php?&tw=1&pmid=27591095 #FOAvip Liver fibrosis results from chronic injury of hepatocytes and activation of Collagen Type I producing myofibroblasts that produce fibrous scar in liver fibrosis. Myofibroblasts are not present in the normal liver but rapidly appear early in experimental and clinical liver injury. The origin of the myofibroblast in liver fibrosis is still unresolved. The possibilities include activation of liver resident cells including portal fibroblasts, hepatic stellate cells, mesenchymal progenitor cells, and fibrocytes recruited from the bone marrow. It is considered that hepatic stellate cells and portal fibroblasts are the major source of hepatic myofibroblasts. In fact, the origin of myofibroblasts differs significantly for chronic liver diseases of different etiologies, such as cholestatic liver disease or hepatotoxic liver disease. Depending on etiology of hepatic injury, the fibrogenic foci might initiate within the hepatic lobule as seen in chronic hepatitis, or primarily affect the portal areas as in most biliary diseases. It has been suggested that activated portal fibroblasts/myofibroblasts work as ?myofibroblasts for cholangiocytes? while hepatic stellate cells work as ?myofibroblast for hepatocytes?. This review will focus on our current understanding of the activated portal fibroblasts/myofibroblasts in cholestatic liver fibrosis. Twit Text FOAVip The Characteristics of Activated Portal Fibroblasts / Myofibroblasts in Liver Fibrosis ????Differentiation http://www.kidney.de/pget.php?&tw=1&pmid=27591095 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27591095 #FOAvip English Wikipedia <ref>{{Cite pmid|27591095}}</ref> The Characteristics of Activated Portal Fibroblasts / Myofibroblasts in Liver Fibrosis #MMPMID27591095 Karin D; Koyama Y; Brenner D; Kisseleva T Differentiation 2016[Sep]; 92 (3): 84-92 PMID27591095show ga Liver fibrosis results from chronic injury of hepatocytes and activation of Collagen Type I producing myofibroblasts that produce fibrous scar in liver fibrosis. Myofibroblasts are not present in the normal liver but rapidly appear early in experimental and clinical liver injury. The origin of the myofibroblast in liver fibrosis is still unresolved. The possibilities include activation of liver resident cells including portal fibroblasts, hepatic stellate cells, mesenchymal progenitor cells, and fibrocytes recruited from the bone marrow. It is considered that hepatic stellate cells and portal fibroblasts are the major source of hepatic myofibroblasts. In fact, the origin of myofibroblasts differs significantly for chronic liver diseases of different etiologies, such as cholestatic liver disease or hepatotoxic liver disease. Depending on etiology of hepatic injury, the fibrogenic foci might initiate within the hepatic lobule as seen in chronic hepatitis, or primarily affect the portal areas as in most biliary diseases. It has been suggested that activated portal fibroblasts/myofibroblasts work as ?myofibroblasts for cholangiocytes? while hepatic stellate cells work as ?myofibroblast for hepatocytes?. This review will focus on our current understanding of the activated portal fibroblasts/myofibroblasts in cholestatic liver fibrosis. äThe Characteristics of Activated Portal Fibroblasts / Myofibroblasts i(epmc).pdf DeepDyve Pubget Overpricing