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10.1080/19336918.2016.1173803 http://scihub22266oqcxt.onion/10.1080/19336918.2016.1173803 C5079401!5079401!27104281     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Adh+Migr 2016 ; 10 (5): 568-75 Nephropedia Template TP {{tp|p=27104281|t=2016. Toward correlating structure and mechanics of platelets |pdf=|usr=}}{{27104281}} gab.com Text Toward correlating structure and mechanics of platelets JO: Cell Adh Migr http://www.kidney.de/pget.php?&tw=1&pmid=27104281 #FOAvip The primary physiological function of blood platelets is to seal vascular lesions after injury and form hemostatic thrombi in order to prevent blood loss. This task relies on the formation of strong cellular-extracellular matrix interactions in the subendothelial lesions. The cytoskeleton of a platelet is key to all of its functions: its ability to spread, adhere and contract. Despite the medical significance of platelets, there is still no high-resolution structural information of their cytoskeleton. Here, we discuss and present 3-dimensional (3D) structural analysis of intact platelets by using cryo-electron tomography (cryo-ET) and atomic force microscopy (AFM). Cryo-ET provides in situ structural analysis and AFM gives stiffness maps of the platelets. In the future, combining high-resolution structural and mechanical techniques will bring new understanding of how structural changes modulate platelet stiffness during activation and adhesion. Twit Text FOAVip Toward correlating structure and mechanics of platelets ????Cell Adh Migr http://www.kidney.de/pget.php?&tw=1&pmid=27104281 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27104281 #FOAvip English Wikipedia <ref>{{Cite pmid|27104281}}</ref> Toward correlating structure and mechanics of platelets #MMPMID27104281 Sorrentino S; Studt JD; Horev MB; Medalia O; Sapra KT Cell Adh Migr 2016[Sep]; 10 (5): 568-75 PMID27104281show ga The primary physiological function of blood platelets is to seal vascular lesions after injury and form hemostatic thrombi in order to prevent blood loss. This task relies on the formation of strong cellular-extracellular matrix interactions in the subendothelial lesions. The cytoskeleton of a platelet is key to all of its functions: its ability to spread, adhere and contract. Despite the medical significance of platelets, there is still no high-resolution structural information of their cytoskeleton. Here, we discuss and present 3-dimensional (3D) structural analysis of intact platelets by using cryo-electron tomography (cryo-ET) and atomic force microscopy (AFM). Cryo-ET provides in situ structural analysis and AFM gives stiffness maps of the platelets. In the future, combining high-resolution structural and mechanical techniques will bring new understanding of how structural changes modulate platelet stiffness during activation and adhesion. äToward correlating structure and mechanics of platelets (epmc).pdf DeepDyve Pubget Overpricing