Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27628668
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 EBioMedicine
2016 ; 12
(ä): 178-188
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Plasmablasts During Acute Dengue Infection Represent a Small Subset of a Broader
Virus-specific Memory B Cell Pool
#MMPMID27628668
Appanna R
; Kg S
; Xu MH
; Toh YX
; Velumani S
; Carbajo D
; Lee CY
; Zuest R
; Balakrishnan T
; Xu W
; Lee B
; Poidinger M
; Zolezzi F
; Leo YS
; Thein TL
; Wang CI
; Fink K
EBioMedicine
2016[Oct]; 12
(ä): 178-188
PMID27628668
show ga
Dengue is endemic in tropical countries worldwide and the four dengue virus
serotypes often co-circulate. Infection with one serotype results in high titers
of cross-reactive antibodies produced by plasmablasts, protecting temporarily
against all serotypes, but impairing protective immunity in subsequent
infections. To understand the development of these plasmablasts, we analyzed
virus-specific B cell properties in patients during acute disease and at
convalescence. Plasmablasts were unrelated to classical memory cells expanding in
the blood during early recovery. We propose that only a small subset of memory B
cells is activated as plasmablasts during repeat infection and that plasmablast
responses are not representative of the memory B cell repertoire after dengue
infection.