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10.1016/j.cub.2016.08.004

http://scihub22266oqcxt.onion/10.1016/j.cub.2016.08.004
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C5076561!5076561!27676308
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suck abstract from ncbi

pmid27676308      Curr+Biol 2016 ; 26 (18): R859-64
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  • Gene Flow and Molecular Innovation in Bacteria #MMPMID27676308
  • Ruzzini AC; Clardy J
  • Curr Biol 2016[Sep]; 26 (18): R859-64 PMID27676308show ga
  • The small molecules produced by environmental bacteria have been mainstays of both chemical and biological research for decades, and some have lead to important therapeutic interventions. These small molecules have been shaped by natural selection as they evolved to fulfill changing functional roles in their native environments. This minireview describes some recent systematic studies providing illustrative examples that involve the acquisition and alteration of genetic information for molecular innovation by bacteria in well-defined environments. Two different bacterial genera are featured, Pseudonocardia and Salinispora, and while the small molecule repertoires of both have benefited from horizontal gene transfer, Pseudonocardia spp. have relied on plasmid-based tactics while Salinispora spp. have relied on chromosomally integrated genomic islands.
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