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10.1597/15-130

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suck abstract from ncbi


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pmid27533493
      Cleft+Palate+Craniofac+J 2016 ; 53 (5 ): 607-13
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  • Resolution of Otitis Media With Effusion in Children With Cleft Palate Followed Through Five Years of Age #MMPMID27533493
  • Alper CM ; Losee JE ; Seroky JT ; Mandel EM ; Richert BC ; Doyle WJ
  • Cleft Palate Craniofac J 2016[Sep]; 53 (5 ): 607-13 PMID27533493 show ga
  • OBJECTIVE: To describe the temporal pattern of otitis media with effusion (OME) resolution for a cohort of nonsyndromic cleft palate children enrolled before palatoplasty and followed through 5 years of age. DESIGN: This is a prospective, longitudinal study of the time course for OME resolution in infants and children with palatal clefts. SETTING: Cleft Palate Craniofacial Center of a tertiary care pediatric hospital. PARTICIPANTS: This study included 52 children with cleft palate (29 boys, 45 white, Veau 1 through 4) who had a Furlow-type palatoplasty between 10 and 24 months of age performed by one of six surgeons. INTERVENTIONS: Standard cleft palate management was supplemented with study visits to the research clinic pre- and postpalatoplasty and then yearly to 6 years of age for assessments of middle ear status by interval history, otoscopy, and tympanometry. MAIN OUTCOME MEASURE: The main outcome measure was age at otitis media resolution defined as the age in years at the first in a sequence of "disease-free" diagnoses not interrupted or followed by any other diagnosis. RESULTS: The cumulative percent OME resolution for ears/children at ages <1, 1, 2, 3, 4, 5 years was 4.1/4.4, 14.3/10.9, 31.6/21.7, 45.9/37.0, 56.1/50.0, and 70.4/60.9%. OME resolution followed a simple linear time curve with slopes of 13.5% (confidence interval [CI] = 12.2% to 14.8%, r(2) = .99) and 11.9% (CI = 10.1% to 13.6%, r(2) = .99) resolutions per year for ears and children, respectively. CONCLUSIONS: There is a natural, age-related pattern of resolution for persistent OME that affects most infants and young children with cleft palate that is not affected by palatoplasty.
  • |Acoustic Impedance Tests [MESH]
  • |Child, Preschool [MESH]
  • |Cleft Palate/*complications [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Infant [MESH]
  • |Longitudinal Studies [MESH]
  • |Male [MESH]
  • |Otitis Media with Effusion/*etiology [MESH]


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