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Resolution of Otitis Media With Effusion in Children With Cleft Palate Followed
Through Five Years of Age
#MMPMID27533493
Alper CM
; Losee JE
; Seroky JT
; Mandel EM
; Richert BC
; Doyle WJ
Cleft Palate Craniofac J
2016[Sep]; 53
(5
): 607-13
PMID27533493
show ga
OBJECTIVE: To describe the temporal pattern of otitis media with effusion (OME)
resolution for a cohort of nonsyndromic cleft palate children enrolled before
palatoplasty and followed through 5 years of age. DESIGN: This is a prospective,
longitudinal study of the time course for OME resolution in infants and children
with palatal clefts. SETTING: Cleft Palate Craniofacial Center of a tertiary care
pediatric hospital. PARTICIPANTS: This study included 52 children with cleft
palate (29 boys, 45 white, Veau 1 through 4) who had a Furlow-type palatoplasty
between 10 and 24 months of age performed by one of six surgeons. INTERVENTIONS:
Standard cleft palate management was supplemented with study visits to the
research clinic pre- and postpalatoplasty and then yearly to 6 years of age for
assessments of middle ear status by interval history, otoscopy, and tympanometry.
MAIN OUTCOME MEASURE: The main outcome measure was age at otitis media resolution
defined as the age in years at the first in a sequence of "disease-free"
diagnoses not interrupted or followed by any other diagnosis. RESULTS: The
cumulative percent OME resolution for ears/children at ages <1, 1, 2, 3, 4, 5
years was 4.1/4.4, 14.3/10.9, 31.6/21.7, 45.9/37.0, 56.1/50.0, and 70.4/60.9%.
OME resolution followed a simple linear time curve with slopes of 13.5%
(confidence interval [CI] = 12.2% to 14.8%, r(2) = .99) and 11.9% (CI = 10.1% to
13.6%, r(2) = .99) resolutions per year for ears and children, respectively.
CONCLUSIONS: There is a natural, age-related pattern of resolution for persistent
OME that affects most infants and young children with cleft palate that is not
affected by palatoplasty.
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