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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Spinal+Cord+Med 2016 ; 39 (2): 240-2 Nephropedia Template TP
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Keratinizing desquamative squamous metaplasia in the kidney of a patient with complex spinal cord injury #MMPMID26864427
Coode-Bate J; Davies MC; Cook I
J Spinal Cord Med 2016[Mar]; 39 (2): 240-2 PMID26864427show ga
Context: Keratinizing desquamative squamous metaplasia (KDSM) of the upper urinary tract was previously thought, but never proven, to represent a premalignant condition. However, no clear guidelines exist regarding the long-term management and follow up once this rare diagnosis has been made. Findings: Patients with spinal cord injury often develop a range of risk factors for malignancy of the urinary tract. We present the first reported case of KDSM in the kidney of a 44-year-old man with spinal cord injury whose complex urological history includes previous augmentation cystoplasty, recurrent calculi, infections and indwelling catheters. Clinical relevance: Recent literature has suggested a move away from the previous mainstay of treatment with radical surgery towards nephron-sparing endoscopic and radiological surveillance. This case highlights the complexity of preserving renal function in a spinal cord injured patient with KDSM of the kidney.