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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Spinal+Cord+Med
2016 ; 39
(2
): 240-2
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Keratinizing desquamative squamous metaplasia in the kidney of a patient with
complex spinal cord injury
#MMPMID26864427
Coode-Bate J
; Davies MC
; Cook I
J Spinal Cord Med
2016[]; 39
(2
): 240-2
PMID26864427
show ga
CONTEXT: Keratinizing desquamative squamous metaplasia (KDSM) of the upper
urinary tract was previously thought, but never proven, to represent a
premalignant condition. However, no clear guidelines exist regarding the
long-term management and follow up once this rare diagnosis has been made.
FINDINGS: Patients with spinal cord injury often develop a range of risk factors
for malignancy of the urinary tract. We present the first reported case of KDSM
in the kidney of a 44-year-old man with spinal cord injury whose complex
urological history includes previous augmentation cystoplasty, recurrent calculi,
infections and indwelling catheters. CLINICAL RELEVANCE: Recent literature has
suggested a move away from the previous mainstay of treatment with radical
surgery towards nephron-sparing endoscopic and radiological surveillance. This
case highlights the complexity of preserving renal function in a spinal cord
injured patient with KDSM of the kidney.