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10.1136/esmoopen-2016-000078 http://scihub22266oqcxt.onion/10.1136/esmoopen-2016-000078 C5070257!5070257!27843628     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       ESMO+Open 2016 ; 1 (4): ä Nephropedia Template TP {{tp|p=27843628|t=2016. Recent advances in the biology of human circulating tumour cells and metastasis |pdf=|usr=}}{{27843628}} gab.com Text Recent advances in the biology of human circulating tumour cells and metastasis JO: ESMO Open http://www.kidney.de/pget.php?&tw=1&pmid=27843628 #FOAvip The development of a metastatic disease is recognised as the cause of death of over 90% of patients diagnosed with cancer. Understanding the biological features of metastasis has been hampered for a long time by the difficulties to study widespread cancerous lesions in patients, and by the absence of reliable methods to isolate viable metastatic cells during disease progression. These difficulties negatively impact on our ability to develop new agents that are tailored to block the spread of cancer. Yet, recent advances in specialised devices for the isolation of circulating tumour cells (CTCs), hand-in-hand with technologies that enable single cell resolution interrogation of their genome and transcriptome, are now paving the way to understanding those molecular mechanisms that drive the formation of metastasis. In this review, we aim to summarise some of the latest discoveries in CTC biology in the context of several types of cancer, and to highlight those findings that have a potential to improve the clinical management of patients with metastatic cancer. Twit Text FOAVip Recent advances in the biology of human circulating tumour cells and metastasis ????ESMO Open http://www.kidney.de/pget.php?&tw=1&pmid=27843628 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27843628 #FOAvip English Wikipedia <ref>{{Cite pmid|27843628}}</ref> Recent advances in the biology of human circulating tumour cells and metastasis #MMPMID27843628 Gkountela S; Szczerba B; Donato C; Aceto N ESMO Open 2016[]; 1 (4): ä PMID27843628show ga The development of a metastatic disease is recognised as the cause of death of over 90% of patients diagnosed with cancer. Understanding the biological features of metastasis has been hampered for a long time by the difficulties to study widespread cancerous lesions in patients, and by the absence of reliable methods to isolate viable metastatic cells during disease progression. These difficulties negatively impact on our ability to develop new agents that are tailored to block the spread of cancer. Yet, recent advances in specialised devices for the isolation of circulating tumour cells (CTCs), hand-in-hand with technologies that enable single cell resolution interrogation of their genome and transcriptome, are now paving the way to understanding those molecular mechanisms that drive the formation of metastasis. In this review, we aim to summarise some of the latest discoveries in CTC biology in the context of several types of cancer, and to highlight those findings that have a potential to improve the clinical management of patients with metastatic cancer. äRecent advances in the biology of human circulating tumour cells and m(epmc).pdf DeepDyve Pubget Overpricing