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10.1084/jem.20160258

http://scihub22266oqcxt.onion/10.1084/jem.20160258
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C5068234!5068234!27670592
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suck abstract from ncbi


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pmid27670592      J+Exp+Med 2016 ; 213 (11): 2399-412
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  • Psoriatic T cells recognize neolipid antigens generated by mast cell phospholipase delivered by exosomes and presented by CD1a #MMPMID27670592
  • Cheung KL; Jarrett R; Subramaniam S; Salimi M; Gutowska-Owsiak D; Chen YL; Hardman C; Xue L; Cerundolo V; Ogg G
  • J Exp Med 2016[Oct]; 213 (11): 2399-412 PMID27670592show ga
  • In psoriasis, IFN-??stimulated mast cells release exosomes containing cytoplasmic PLA2 that are transferred to CD1a-expressing cells and generate neolipid antigens which induce the production of IL-22 and IL-17A by CD1a-reactive T cells.
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