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10.1002/wrna.1332 http://scihub22266oqcxt.onion/10.1002/wrna.1332 C5066686!5066686!26821858     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Wiley+Interdiscip+Rev+RNA 2016 ; 7 (4): 438-54 Nephropedia Template TP {{tp|p=26821858|t=2016. The Ccr4?Not complex is a key regulator of eukaryotic gene expression |pdf=|usr=}}{{26821858}} gab.com Text The Ccr4 Not complex is a key regulator of eukaryotic gene expression JO: Wiley Interdiscip Rev RNA http://www.kidney.de/pget.php?&tw=1&pmid=26821858 #FOAvip The Ccr4?Not complex is a multisubunit complex present in all eukaryotes that contributes to regulate gene expression at all steps, from production of messenger RNAs (mRNAs) in the nucleus to their degradation in the cytoplasm. In the nucleus it influences the post?translational modifications of the chromatin template that has to be remodeled for transcription, it is present at sites of transcription and associates with transcription factors as well as with the elongating polymerase, it interacts with the factors that prepare the new transcript for export to the cytoplasm and finally is important for nuclear quality control and influences mRNA export. In the cytoplasm it is present in polysomes where mRNAs are translated and in RNA granules where mRNAs will be redirected upon inhibition of translation. It influences mRNA translatability, and is needed during translation, on one hand for co?translational protein interactions and on the other hand to preserve translation that stalls. It is one of the relevant players during co?translational quality control. It also interacts with factors that will repress translation or induce mRNA decapping when recruited to the translating template. Finally, Ccr4?Not carries deadenylating enzymes and is a key player in mRNA decay, generic mRNA decay that follows normal translation termination, co?translational mRNA decay of transcripts on which the ribosomes stall durably or which carry a non?sense mutation and finally mRNA decay that is induced by external signaling for a change in genetic programming. Ccr4?Not is a master regulator of eukaryotic gene expression. WIREs RNA 2016, 7:438?454. doi: 10.1002/wrna.1332For further resources related to this article, please visit the WIREs website. Twit Text FOAVip The Ccr4 Not complex is a key regulator of eukaryotic gene expression ????Wiley Interdiscip Rev RNA http://www.kidney.de/pget.php?&tw=1&pmid=26821858 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26821858 #FOAvip English Wikipedia <ref>{{Cite pmid|26821858}}</ref> The Ccr4?Not complex is a key regulator of eukaryotic gene expression #MMPMID26821858 Collart MA Wiley Interdiscip Rev RNA 2016[Jul]; 7 (4): 438-54 PMID26821858show ga The Ccr4?Not complex is a multisubunit complex present in all eukaryotes that contributes to regulate gene expression at all steps, from production of messenger RNAs (mRNAs) in the nucleus to their degradation in the cytoplasm. In the nucleus it influences the post?translational modifications of the chromatin template that has to be remodeled for transcription, it is present at sites of transcription and associates with transcription factors as well as with the elongating polymerase, it interacts with the factors that prepare the new transcript for export to the cytoplasm and finally is important for nuclear quality control and influences mRNA export. In the cytoplasm it is present in polysomes where mRNAs are translated and in RNA granules where mRNAs will be redirected upon inhibition of translation. It influences mRNA translatability, and is needed during translation, on one hand for co?translational protein interactions and on the other hand to preserve translation that stalls. It is one of the relevant players during co?translational quality control. It also interacts with factors that will repress translation or induce mRNA decapping when recruited to the translating template. Finally, Ccr4?Not carries deadenylating enzymes and is a key player in mRNA decay, generic mRNA decay that follows normal translation termination, co?translational mRNA decay of transcripts on which the ribosomes stall durably or which carry a non?sense mutation and finally mRNA decay that is induced by external signaling for a change in genetic programming. Ccr4?Not is a master regulator of eukaryotic gene expression. WIREs RNA 2016, 7:438?454. doi: 10.1002/wrna.1332For further resources related to this article, please visit the WIREs website. äThe Ccr4?Not complex is a key regulator of eukaryotic gene expression (epmc).pdf DeepDyve Pubget Overpricing