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10.1073/pnas.1611324113 http://scihub22266oqcxt.onion/10.1073/pnas.1611324113 C5056055!5056055!27647912     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2016 ; 113 (40): 11190-5 Nephropedia Template TP {{tp|p=27647912|t=2016. Vascular smooth muscle cell durotaxis depends on extracellular matrix composition |pdf=|usr=}}{{27647912}} gab.com Text Vascular smooth muscle cell durotaxis depends on extracellular matrix composition JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=27647912 #FOAvip Many cell types have been observed to migrate toward stiffer regions of mechanical gradients in a process termed durotaxis. Tissue stiffness gradients are being discovered in an increasing number of diseases, including cancer and fibrotic diseases. However, the role of ECM composition, which often changes in diseased tissues with stiffness, in directing this behavior has not previously been investigated. To understand how stiffness gradients and changing matrix composition may affect cell migration in disease, we have designed a mechanical gradient platform that allows for independent control of absolute stiffness, gradient steepness, and ECM coating. We demonstrate that smooth muscle cells will undergo durotaxis on mechanical gradients coated with fibronectin but not laminin. Twit Text FOAVip Vascular smooth muscle cell durotaxis depends on extracellular matrix composition ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=27647912 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27647912 #FOAvip English Wikipedia <ref>{{Cite pmid|27647912}}</ref> Vascular smooth muscle cell durotaxis depends on extracellular matrix composition #MMPMID27647912 Hartman CD; Isenberg BC; Chua SG; Wong JY Proc Natl Acad Sci U S A 2016[Oct]; 113 (40): 11190-5 PMID27647912show ga Many cell types have been observed to migrate toward stiffer regions of mechanical gradients in a process termed durotaxis. Tissue stiffness gradients are being discovered in an increasing number of diseases, including cancer and fibrotic diseases. However, the role of ECM composition, which often changes in diseased tissues with stiffness, in directing this behavior has not previously been investigated. To understand how stiffness gradients and changing matrix composition may affect cell migration in disease, we have designed a mechanical gradient platform that allows for independent control of absolute stiffness, gradient steepness, and ECM coating. We demonstrate that smooth muscle cells will undergo durotaxis on mechanical gradients coated with fibronectin but not laminin. äVascular smooth muscle cell durotaxis depends on extracellular matrix (epmc).pdf DeepDyve Pubget Overpricing