Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Ann+N+Y+Acad+Sci 2016 ; 1374 (1): 123-31 Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Emerging targets for treating sulfur mustard-induced injuries #MMPMID27285828
Ahmad S; Ahmad A
Ann N Y Acad Sci 2016[Jun]; 1374 (1): 123-31 PMID27285828show ga
Sulfur mustard (SM, bis- (2-chlororethyl) sulfide) is a highly reactive, potent warfare agent that has currently reemerged as a major threat to military and civilians. Exposure to SM is often fatal primarily due to pulmonary injuries and complications caused by its inhalation. Profound inflammation, hypercoagulation and oxidative stress are the hallmarks that define SM-induced pulmonary toxicities. Despite advances, effective therapies are still limited. This current review focuses on inflammatory and coagulation pathways that influence the airway pathophysiology of SM poisoning and highlights the complexity of developing an effective therapeutic target.