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Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Cell+Biol 2016 ; 214 (7): 817-30 Nephropedia Template TP
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Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization #MMPMID27646274
West JA; Mito M; Kurosaka S; Takumi T; Tanegashima C; Chujo T; Yanaka K; Kingston RE; Hirose T; Bond C; Fox A; Nakagawa S
J Cell Biol 2016[Sep]; 214 (7): 817-30 PMID27646274show ga
Paraspeckles are nuclear bodies built on the long noncoding RNA Neat1. Using structural illumination microscopy, West et al. analyze the organization of paraspeckles at the submicron scale and show that paraspeckle proteins are arranged around bundles of Neat1, forming core-shell spheroidal structures dependent on the RNA binding protein Fus.