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10.1002/eji.201546262 http://scihub22266oqcxt.onion/10.1002/eji.201546262 C5036921!5036921!27139187     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Immunol 2016 ; 46 (7): 1592-9 Nephropedia Template TP {{tp|p=27139187|t=2016. Efferocytosis as a regulator of macrophage chemokine receptor expression and polarization |pdf=|usr=}}{{27139187}} gab.com Text Efferocytosis as a regulator of macrophage chemokine receptor expression and polarization JO: Eur J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=27139187 #FOAvip Efferocytosis has been suggested to promote macrophage resolution programs that are dependent on motility and emigration, however, few studies have addressed directed migration in resolving macrophages. In this report, we hypothesized that efferocytosis would induce differential chemokine receptor expression. Polarized macrophage populations, including macrophages actively engaged in efferocytosis, were characterized by PCR array and traditional transwell motility assays. We identified specific up-regulation of chemokine receptor CXCR4 on both mouse and human macrophages and characterized in vivo expression of CXCR4 in a resolving model of murine peritonitis. Using adoptive transfer and AMD3100 blocking, we confirmed a role for CXCR4 in macrophage egress to draining lymphatics. Collectively these data provide an important mechanistic link between efferocytosis and macrophage emigration. Twit Text FOAVip Efferocytosis as a regulator of macrophage chemokine receptor expression and polarization ????Eur J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=27139187 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27139187 #FOAvip English Wikipedia <ref>{{Cite pmid|27139187}}</ref> Efferocytosis as a regulator of macrophage chemokine receptor expression and polarization #MMPMID27139187 Angsana J; Chen J; Liu L; Haller CA; Chaikof EL Eur J Immunol 2016[Jul]; 46 (7): 1592-9 PMID27139187show ga Efferocytosis has been suggested to promote macrophage resolution programs that are dependent on motility and emigration, however, few studies have addressed directed migration in resolving macrophages. In this report, we hypothesized that efferocytosis would induce differential chemokine receptor expression. Polarized macrophage populations, including macrophages actively engaged in efferocytosis, were characterized by PCR array and traditional transwell motility assays. We identified specific up-regulation of chemokine receptor CXCR4 on both mouse and human macrophages and characterized in vivo expression of CXCR4 in a resolving model of murine peritonitis. Using adoptive transfer and AMD3100 blocking, we confirmed a role for CXCR4 in macrophage egress to draining lymphatics. Collectively these data provide an important mechanistic link between efferocytosis and macrophage emigration. äEfferocytosis as a regulator of macrophage chemokine receptor expressi(epmc).pdf DeepDyve Pubget Overpricing