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10.1016/j.drudis.2016.05.011

http://scihub22266oqcxt.onion/10.1016/j.drudis.2016.05.011
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C5035580!5035580!27238384
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suck abstract from ncbi


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pmid27238384      Drug+Discov+Today 2016 ; 21 (9): 1489-94
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  • Biochemical and biomechanical drivers of cancer cell metastasis, drug response and nanomedicine #MMPMID27238384
  • Yoshii T; Geng Y; Peyton S; Mercurio AM; Rotello VM
  • Drug Discov Today 2016[Sep]; 21 (9): 1489-94 PMID27238384show ga
  • Metastasis, drug resistance and recurrence in cancer are regulated by the tumor microenvironment. This review describes recent advances in understanding how cancer cells respond to extracellular environmental cues via integrins, how to build engineered microenvironments to study these interactions in vitro and how nanomaterials can be used to detect and target tumor microenvironments.
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