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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Drug+Discov+Today 2016 ; 21 (9): 1489-94 Nephropedia Template TP
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Biochemical and biomechanical drivers of cancer cell metastasis, drug response and nanomedicine #MMPMID27238384
Yoshii T; Geng Y; Peyton S; Mercurio AM; Rotello VM
Drug Discov Today 2016[Sep]; 21 (9): 1489-94 PMID27238384show ga
Metastasis, drug resistance and recurrence in cancer are regulated by the tumor microenvironment. This review describes recent advances in understanding how cancer cells respond to extracellular environmental cues via integrins, how to build engineered microenvironments to study these interactions in vitro and how nanomaterials can be used to detect and target tumor microenvironments.